Results 111 to 120 of about 1,353,067 (263)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Structural models of viral insulin-like peptides and their analogs. [PDF]
Proteins, 2023 Gorai B, Vashisth H.
europepmc +1 more source
Механика машин, механизмов и материалов, 2008 The deformation processes of metal-polymer copper-polytetrafluoroethylene powder system have been investigated by computer methods. The structural models have been developed, the values of displacements and stresses have been defined.
T.V. Ryabchenko +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Marginal structural models for multilevel clustered data. [PDF]
Biostatistics, 2022 Wu Y, Langworthy B, Wang M.
europepmc +1 more source
STRUCTURAL MODELS OF TERM FORMATION IN UKRAINIAN IT DISCOURSE: TRANSFORMATIONS AND TRENDS
Вісник Київського національного лінгвістичного університету. Серія: ФілологіяThe article presents a comprehensive analysis of the structural models used in the formation of terms in modern Ukrainian IT discourse and traces their transformation under the influence of the English language and current trends in information ...
O. B. Lysychenko, Kh. B. Melko
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Improved computational epitope profiling using structural models identifies a broader diversity of antibodies that bind to the same epitope. [PDF]
Front Mol Biosci, 2023 Spoendlin FC +5 more
europepmc +1 more source