Results 171 to 180 of about 1,353,067 (263)

Advancing fine branch biomass estimation with lidar and structural models. [PDF]

Ann Bot
Millan M, Bonnet A, Dauzat J, Vezy R.
europepmc   +1 more source

Testing structural models of psychopathology at the genomic level. [PDF]

World Psychiatry, 2020
Waldman ID, Poore HE, Luningham JM, Yang J.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Current Landscape of Psychologists in Academic Health Centers: Roles and Structural Models. [PDF]

J Clin Psychol Med Settings
Moore MB, Gilrain K, Brosig C, Leffler JM, Gupta S, Fizur P.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Structural Models for a Series of Allosteric Inhibitors of IGF1R Kinase. [PDF]

Int J Mol Sci
Verma J, Vashisth H.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Folding the human proteome using BioNeMo: A fused dataset of structural models for machine learning purposes. [PDF]

Sci Data
Hetmann M, Parigger L, Sirelkhatim H, Stern A, Krassnigg A, Gruber K, Steinkellner G, Ruau D, Gruber CC.   +8 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Multiply robust estimation of marginal structural models in observational studies subject to covariate-driven observations. [PDF]

Biometrics
Coulombe J, Yang S.
europepmc   +1 more source