The missing link: covalent linkages in structural models. [PDF]
Nicholls RA +7 more
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Structural models for spreading and scaling digital health initiatives: A scoping review protocol. [PDF]
Laur C +10 more
europepmc +1 more source
Use of structural models to elucidate the occurrence of falls among older adults according to abdominal obesity: a cross-sectional study. [PDF]
Monteiro ELF +4 more
europepmc +1 more source
Convex Formulation for Regularized Estimation of Structural Equation\n Models [PDF]
Anupon Pruttiakaravanich +1 more
openalex +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Efficient global accuracy estimation for protein complex structural models using multi-view representation learning. [PDF]
Liu D +7 more
europepmc +1 more source
Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes. [PDF]
Keller GLJ, Weiss LI, Baker BM.
europepmc +1 more source
Game of LLMs: Discovering Structural Constructs in Activities using Large Language Models [PDF]
Shruthi K. Hiremath, Thomas Ploetz
openalex +1 more source

