Marginal structural models for quantifying the causal effects of exposure to ambient air pollution on progression of CT emphysema in the MESA lung and MESA air studies. [PDF]
Malinsky D +11 more
europepmc +1 more source
Use of structural models to elucidate the occurrence of falls among older adults according to abdominal obesity: a cross-sectional study. [PDF]
Monteiro ELF +4 more
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Quasi-Maximum Likelihood for Estimating Structural Models. [PDF]
Ben-Abdellatif M +3 more
europepmc +1 more source
Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes. [PDF]
Keller GLJ, Weiss LI, Baker BM.
europepmc +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Adherence to the Dietary Approaches to Stop Hypertension score and cardiovascular disease risk in Korean adults: a prospective cohort study using marginal structural models. [PDF]
Kim SH, Kim H, Shin D.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Evaluation of the structural models of the human reference proteome: AlphaFold2 versus ESMFold. [PDF]
Manfredi M +3 more
europepmc +1 more source

