Results 51 to 60 of about 3,926,912 (305)

Integration of Measures of Functional and Structural MRI

, 2009
Recent years have seen a renewed interest in brain anatomy in the neuroimaging community. Developments in techniques for structural MR acquisition and analysis have opened new opportunities for structural mapping of the living human brain. For example, high-resolution MR imaging can be used for "in vivo histology", techniques such as voxel-based ...
Johansen-Berg, H, Behrens, T, Jbabdi, S, Watkins, K   +3 more
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Structural co-modulation: An individualized measure of inter-component interactions in source-based morphometry

NeuroImage
Source-based morphometry (SBM) is a powerful multivariate method for identifying covarying structural brain networks. However, standard SBM provides only a single loading value per component for each subject, which limits the characterization of ...
Aline Kotoski, Najme Soleimani, Sir-Lord Wiafe, Spencer Kinsey, Vince Calhoun   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

High resolution MRI of the brain at 4.7 Tesla using fast spin echo imaging [PDF]

, 2003
Over recent years, high field MR scanners (3 T and above) have become increasingly widespread due to potential advantages such as higher signal-to-noise ratio.
Thomas, D.L., Roberts, S., Yousry, T.A., Ordidge, R.J., De Vita, E., Parkes, H.G., Kinchesh, P., Parkes, H., Shmueli, K., Yousry, T., Turner, R., Thomas, D., Ordidge, R.   +12 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The DAMASK trial protocol: a pragmatic randomised trial to evaluate whether GPs should have direct access to MRI for patients with suspected internal derangement of the knee [PDF]

, 2006
Background: Though new technologies like Magnetic Resonance Imaging (MRI) may be accurate, they often diffuse into practice before thorough assessment of their value in diagnosis and management, and of their effects on patient outcome and costs.
Brealey, Stephen, Stephen D Brealey, T Russell, Ian, Wadsworth, V, Gillan, MG, Fiona Fylan, Maureen GC Gillan, Helen Cox, Houston, H, Hendry, Maggie, Gillan, Maureen, Maggie Hendry, Christine Atwell, Torgerson David, Orchard, Jo, King, David C., Valerie Wadsworth, Cox Helen, Atwell, Christine, Gillan Maureen GC, Brealey, Stephen D., Robling Michael, Helen Houston, Ian T Russell, Russell, Ian, Fylan, Fiona, Cross, Ben, Robling, M, Gilbert, Fiona, Wilkinson Clare, Andrew Garratt, Clare Wilkinson, Michael Robling, Bryan, Stirling, Jo Orchard, David King, Wilkinson, Clare, Brealey, Stephen D, Cox, Helen, Gillan, Maureen G. C., Gilbert, Fiona J, Coulton, Simon, Bryan, S, Coulton, S, Russell, IT, Orchard Jo, Cox, H, Gilbert, Fiona J., Fylan Fiona, Ben Cross, Wilkinson, C, Garratt, Andrew, Coulton Simon, Cross, B, Wadsworth Valerie, Kerenza Hood, Morton, Veronica, Gillan, Maureen G C, Garratt Andrew, Cross Ben, Houston Helen, Houston, Helen, King David, Gilbert, FJ, David Torgerson, Atwell Christine, Hendry, M, Morton Veronica, Torgerson, David J., Russell Ian T, Wadsworth, Valerie, Fiona J Gilbert, Morton, V, Torgerson, D, King, D, Atwell, C, Torgerson, David, Stirling Bryan, Robling, Michael, Simon Coulton, Brealey, SD, Brealey Stephen D, Hood, K, King, David, Garratt, A, Orchard, J, Fylan, F, Hendry Maggie, Bryan Stirling, Gilbert Fiona J, Hood, Kerenza, Hood Kerenza, Veronica Morton   +92 more
core   +3 more sources

The Combination of Functional and Structural MRI Is a Potential Screening Tool in Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2018
Introduction: This study aimed to survey the discrimination power of parameters from cerebrospinal fluid (CSF) biomarkers, fluorodeoxyglucose uptake on PET (FDG-PET), structural magnetic resonance imaging (MRI), and functional MRI in high- and low-risk ...
Chun-Chao Huang, Chun-Chao Huang, Chun-Chao Huang, Chun-Chao Huang, Wei-Ming Huang, Wei-Ming Huang, Wei-Ming Huang, Chia-Hung Chen, Chia-Hung Chen, Chia-Hung Chen, Zong-Yi Jhou, Zong-Yi Jhou, Zong-Yi Jhou, The Alzheimer’s Disease Neuroimaging Initiative, Ching-Po Lin, Ching-Po Lin, Ching-Po Lin   +16 more
doaj   +1 more source

Multi-Channel 4D Parametrized Atlas of Macro- and Microstructural Neonatal Brain Development

Frontiers in Neuroscience, 2021
Structural (also known as anatomical) and diffusion MRI provide complimentary anatomical and microstructural characterization of early brain maturation.
Alena Uus, Irina Grigorescu, Maximilian Pietsch, Dafnis Batalle, Dafnis Batalle, Daan Christiaens, Daan Christiaens, Emer Hughes, Jana Hutter, Lucilio Cordero Grande, Lucilio Cordero Grande, Anthony N. Price, Jacques-Donald Tournier, Mary A. Rutherford, Serena J. Counsell, Joseph V. Hajnal, Joseph V. Hajnal, A. David Edwards, Maria Deprez   +18 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source