Results 111 to 120 of about 1,128,803 (283)

Modeling, Analysis, and Optimization Issues for Large Space Structures [PDF]

Topics concerning the modeling, analysis, and optimization of large space structures are discussed including structure-control interaction, structural and structural dynamics modeling, thermal analysis, testing, and ...
Amos, A. K., Pinson, L. D., Venkayya, V. B.   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Data-driven modeling on anisotropic mechanical behavior of brain tissue with internal pressure

Defence Technology
Brain tissue is one of the softest parts of the human body, composed of white matter and grey matter. The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function.
Zhiyuan Tang, Yu Wang, Khalil I. Elkhodary, Zefeng Yu, Shan Tang, Dan Peng   +5 more
doaj   +1 more source

Block-Coordinate Frank-Wolfe Optimization for Structural SVMs

, 2013
We propose a randomized block-coordinate variant of the classic Frank-Wolfe algorithm for convex optimization with block-separable constraints. Despite its lower iteration cost, we show that it achieves a similar convergence rate in duality gap as the ...
Jaggi, Martin, Lacoste-Julien, Simon, Pletscher, Patrick, Schmidt, Mark   +3 more
core   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Integrated design optimization research and development in an industrial environment [PDF]

An overview is given of a design optimization project that is in progress at the GE Research and Development Center for the past few years. The objective of this project is to develop a methodology and a software system for design automation and ...
German, Marjorie D., Kumar, V., Lee, S.-J.   +2 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Enhancement effect of casing on underwater explosion shock wave and bubble

Applied Ocean Research
The casing is a critical design factor for underwater weapons, significantly influencing the energy output of underwater explosion (UNDEX) charges.
Zhifan Zhang, Jingyuan Zhang, Hailong Li, Gangwei Liu, Longkan Wang, Guiyong Zhang   +5 more
doaj   +1 more source

Optimum pressure vessel design based on fracture mechanics and reliability criteria [PDF]

Optimization design methods for spacecraft structural systems and ...
Heer, E., Yang, J.-N.
core   +1 more source