Results 91 to 100 of about 363,839 (268)
Applied Ocean ResearchThis study uses experimental methods to investigate the damage characteristics of typical underwater structures under synchronous array charge underwater explosions. Small-scale underwater explosion tests are conducted in a water tank to study the damage
Zhifan Zhang +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Case Studies in Thermal EngineeringPorous media are widely used in scientific research and engineering applications, where the effective thermal conductivity (ETC) serves as a critical thermo-physical parameter governing heat transfer behaviors.
Kun Liu +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
EnergiesAirborne Wind Energy (AWE) systems offer benefits such as high altitude access to stronger and more stable winds, reduced environmental impact, and cost effective infrastructure.
Yanjun Lv +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
High-viscosity microenvironment inhibits endocytosis of drug-loaded nanoparticles in cancer cells
Nano ResearchDrug-loaded nanoparticles (DLNPs) enhance intracellular drug accumulation through endocytosis and are widely used in chemotherapy research. Despite progress, the therapeutic efficacy of DLNPs remains limited due to the complexity of the in vivo ...
Guanlin Zhou, Chengwei Wu, Wei Zhang
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Data-driven modeling on anisotropic mechanical behavior of brain tissue with internal pressure
Defence TechnologyBrain tissue is one of the softest parts of the human body, composed of white matter and grey matter. The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function.
Zhiyuan Tang +5 more
doaj +1 more source