Results 101 to 110 of about 5,411,731 (260)
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Structural optimization based on internal energy distribution
Structural optimization is a valuable tool to improve the performance of products, but it is in general expensive to perform due to the required extensive number of function evaluations.
Oman, Michael,, Nilsson, Larsgunnar,
core +1 more source
Carbon fiber reinforced thermoset composites (CFRP) have demonstrated significant potential for industrial applications. However, their permanent cross-linked networks pose challenges for reprocessing, repairing, and recycling.
Mei Fang +6 more
doaj +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
This study uses experimental methods to investigate the damage characteristics of typical underwater structures under synchronous array charge underwater explosions. Small-scale underwater explosion tests are conducted in a water tank to study the damage
Zhifan Zhang +4 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
During the casting process and solidification of ductile iron castings, a heterogeneous microstructure is formed throughout the casting. This distribution is strongly influenced by the item geometry and the process related factors, as chemical ...
Johansson, Joel, +11 more
core +1 more source
The energy absorption capacity of a novel dual-sub-fold Miura foldcore subjected to axial crushing
A modified Miura foldcore geometry was developed by introducing sub-folds into the cell walls of a conventional Miura foldcore. Similar to other sub-fold Miura foldcores, stable plastic hinge lines were generated at sub-fold sites under the guidance of ...
Caihua Zhou +4 more
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
The paper presents an approach for simultaneous optimization of structural mass and reliability in discrete truss structures. In addition to member sizing, the selection of an optimal topology from a pre-specified ground structure is a feature of the ...
Hajela, Prabhat +3 more
core +1 more source

