Results 91 to 100 of about 3,920,669 (319)

Behaviour of steel sheeting connections with self-drilling screws under variable loading

Open Engineering, 2020
Connections made by self-drilling screws are often used in steel cold-formed structures and sheeting. Their structural properties, such as resistance, flexibility and ductility are obtained by testing under monotonically increasing loading and can ...
Budziński Rafał, Ślęczka Lucjan
doaj   +1 more source

Structural and magnetic properties of MnCo1-xFexSi alloys

, 2015
The crystal structures, martensitic structural transitions and magnetic properties of MnCo1-xFexSi (0
Chen, J. H., Liu, E. K., Qi, X., Wang, W. H., Wei, Z. Y., Wu, G. H.   +5 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Preparation and physical properties of a Cr3Al film with a DO3 structure

IUCrJ, 2019
A Cr3Al compound with a DO3 structure has previously been predicted to be nearly half metal and a promising spintronics material; however, its synthesis has not been reported.
W. Q. Zhao, X. F. Dai, X. M. Zhang, Z. J. Mo, X. T. Wang, G. F. Chen, Z. X. Cheng, G. D. Liu   +7 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Advances in the extraction, purification, structural characterization, and elucidation of the biological functions of polysaccharides from Hericium erinaceus

Frontiers in Nutrition
Hericium erinaceus has a high food and ornamental value and considerable benefits upon consumption and in research. The high polysaccharide content in H. erinaceus gives this fungus unique physiological functions and a smooth, palatable texture; notably,
Panling Yu, Panling Yu, Jianshuai Ma, Jianshuai Ma, Lin Yang, Qin Dong, Changxia Yu, Lei Zha, Baoting Xu, Baoting Xu, Yan Zhao   +10 more
doaj   +1 more source

Influence of argon beam irradiation at different temperatures on the structural properties of Cu/Fe bilayers [PDF]

, 1996
Gustavo A. Echeverría, J. Desimoni, R. C. Mercader, G. Punte   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

O campo organizacional e a adoção de práticas estratégicas: revisitando o modelo de Whittington

Cadernos EBAPE.BR
Neste ensaio teórico, tem-se como objetivo desenvolver um modelo conceitual que possibilite relacionar os diferentes níveis de estratégia de forma a promover a integração entre as perspectivas institucional e de estratégia como prática, com mediação da ...
Silvana Anita Walter, Paulo Otávio Mussi Augusto, Valéria Silva da Fonseca   +2 more
doaj   +1 more source