Results 71 to 80 of about 9,672,449 (304)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tight-Binding Investigation of Structural and Vibrational Properties of Graphene-Single Wall Carbon Nanotube Junctions [PDF]
, 2020 Hybrid carbon nanostructures based on single walled carbon nanotubes (SWNT) and single layer graphene (SLG) are drawing much attention lately for their applications in a range of efficient hybrid devices.
Anshu, Gaur, Juhi, Srivastava
core +1 more source
Beilstein Journal of Nanotechnology, 2021 The influence of film thickness on the structural and optical properties of silicon dioxide (SiO2) and zinc oxide (ZnO) thin films deposited by radio frequency magnetron sputtering on quartz substrates was investigated.
Petronela Prepelita +2 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties
, 2022 The effect of different branching types of glycosylation on the structure and dynamics of the horseradish peroxidase (HRP) and an engineered split horseradish peroxidase (sHRP) was studied using all-atom molecular dynamics (MD) simulations.
Mutter, Natalie; orcid: +13 more
core +1 more source
Open Chemistry, 2023 The objective of this study is to increase the natural clay mineral-based bricks’ ability to shield γ-rays without the use of external doping materials. Six brick samples were consequently developed at various pressure rates (PRs).
Mahmoud K. A., Marashdeh M. W.
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
High-rise structural property identification
, 2022 Wind-induced vibrations are an important aspect in high-rise building design. The structural properties that influence vibrations are the mass and stiffness of the building and the foundation.
Geurts, C.P.W. +2 more
core
Development of Branched ZnO Microrods: A Comprehensive Structural and Optical Characterization [PDF]
Iranian Journal of Materials Science and EngineeringIn this study, a novel three-step method for the synthesis of ZnO and branched ZnO microrods was developed. Numerous techniques were used to analyze the obtained samples: photoluminescence (PL) spectroscopy, raman spectroscopy, fourier transform infrared
ines dhifallah +6 more
doaj