Results 91 to 100 of about 9,672,449 (304)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

DESORPTION OF Te CAPPING LAYER FROM ZnTe (100): AUGER SPECTROSCOPY, LOW-ENERGY ELECTRON DIFFRACTION AND SCANNING TUNNELING MICROSCOPY

Journal of Fundamental and Applied Sciences, 2016
The influence of the annealing temperature to desorb a protective Te capping layer of the zinc telluride (ZnTe (100)) surface was investigated. The surface reconstruction of the ZnTe (100) upon the removal of a Te capping layer grown by the molecular ...
K. K. Sossoe, M. M. Dzagli, A. Sylla, B. Grandidier, A. M. Mohou, T .J. Zoueu, S. Toure   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Studies on the properties of cdS films deposited from pH-controlled growth solutions [PDF]

Materials Research, 2013
In this work we have studied the properties of CdS films obtained by the chemical bath deposition technique. We studied the influence of pH control of the reaction solution on the structural and optical properties of chemically deposited CdS films.
M.B. Ortuño-López, R. Ochoa-Landín, M.G. Sandoval-Paz, M. Sotelo-Lerma, M. Flores-Acosta, R. Ramírez-Bon   +5 more
doaj  

Topological Properties of Event Structures

Electronic Notes in Theoretical Computer Science, 2009
Motivated by the nice labelling problem for event structures, we study the topological properties of the associated graphs. For each n⩾0, we exhibit a graph Gn that cannot occur on an antichain as a subgraph of the graph of an event structure of degree n .
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

On the Evaluation of the Mechanical Behaviour of Structural Glass Elements [PDF]

, 2005
Glass can be considered to be a high-technology engineering material with a multifunctional potential for structural applications. However, the conventional approach to the use of glass is often based only on its properties of transparency and ...
Teixeira-Dias, F., Costa, S., Miranda, M., Varum, H.   +3 more
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Understanding the first steps of the complement classical pathway: Structural studies on C1-antibody complexes [PDF]

, 2018
The complement system is a complex network of plasma and membrane-associated proteins, which can produce effective immune responses to infectious micro-organisms. Deficiencies of complement proteins cause diseases like systemic lupus erythematosus (SLE),
Sub Crystal and Structural Chemistry, Crystal and Structural Chemistry, Ugurlar, D.   +2 more
core