Results 51 to 60 of about 9,672,449 (304)

Structural Properties of the Meniscal Roots

The American Journal of Sports Medicine, 2014
Background: Current surgical techniques for meniscal root repair reattach the most prominent, dense portion of the meniscal root and fail to incorporate recently identified peripheral, supplemental attachment fibers. The contribution of supplemental fibers to the biomechanical properties of native meniscal roots
Ellman, Michael B., LaPrade, Christopher M., Smith, Sean D., Rasmussen, Matthew T., Engebretsen, Lars, Wijdicks, Coen A., LaPrade, Robert F.   +6 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Forecasting mechanical properties of steel structures through dynamic metaheuristic optimization for adaptive machine learning

Journal of Civil Engineering and Management
Machine learning (ML) presents a promising method for predicting mechanical properties in structural engineering, particularly within complex nonlinear structures under extreme conditions.
Ngoc-Mai Nguyen, Jui-Sheng Chou
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Design and structural characterisation of olfactomedin-1 variants as tools for functional studies [PDF]

, 2019
Background Olfactomedin-1 (Olfm1; also known as Noelin or Pancortin) is a highly-expressed secreted brain and retina protein and its four isoforms have different roles in nervous system development and function.
Sub Crystal and Structural Chemistry, Van den Hoek, H., Crystal and Structural Chemistry, Janssen, Bert J. C., Pronker, M., Van Den Hoek, Hugo, Janssen, B., Pronker, Matti F.   +7 more
core   +2 more sources

Spectroscopic and Microscopic Analysis of Apple Pectins

Molecules
Apple pomace pectins, extracted using various methods (water, cellulase, arabinase, and arabinase with mannanase), and commercial apple pectin were studied, analyzing their morphology and chemical structure.
Agata Serrafi, Agnieszka Wikiera, Konrad Cyprych, Magdalena Malik   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Structural-Acoustic Properties of Flexible Rectangular Boxes

, 2018
Rectangular box-like structures are used widely in a large number of engineering applications, e.g. as elements of railway carriages, heavy goods vehicles, buildings, civil engineering constructions, etc. Although flexible rectangular boxes represent one
Victor Krylov (1252356), V.B. Georgiev (5895040)   +1 more
core   +1 more source