Results 101 to 110 of about 3,920,669 (319)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Comparative Phase Evolution, Morphological and Optical Analysis of Partially Stabilized Zirconia Ceramics

Studia Universitatis Babes-Bolyai Chemia
Partially stabilized zirconia (PSZ) ceramics are one of the most important materials used for different applications like thermal barrier coatings, refractories, oxygen-permeating membranes, and dental and bone implants.
Claudia Andreea COJAN, Réka BARABÁS, Marieta MUREȘAN-POP, Liliana BIZO   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Composite materials based on Zinc sulfide and Zinc oxide: structural and biocidal properties

Annals of Mechnikov's Institute, 2020
Introduction. The widespread use of drugs with antimicrobial action has led to the formation of microorganism resistance against wide range of antibiotics.
LB Sukhodub, G Khrystian, LF Sukhodub, N Shulga, A Meshkov, V Kazmirchuk, A Martynov   +6 more
doaj  

SmS/EuS/SmS Tri-Layer Thin Films: The Role of Diffusion in the Pressure Triggered Semiconductor-Metal Transition

Nanomaterials, 2019
While SmS thin films show an irreversible semiconductor-metal transition upon application of pressure, the switching characteristics can be modified by alloying with other elements, such as europium.
Andreas Sousanis, Dirk Poelman, Philippe F. Smet   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Influence of Different Dehairing Methods on the Structural and Functional Properties of Cowhide Gelatin

Shipin gongye ke-ji
The influence of different dehairing methods on the yield, amino acid composition, secondary structure, gel strength, emulsification, and foaming properties of cowhide gelatin was analyzed. Dehairing methods including hot scalding, enzyme treatment, high-
Jiakun GAO, Jing NING, Zheng ZHANG, Xuejun LIU   +3 more
doaj   +1 more source

The effect of a plasticizing admixture on the properties of hardened concrete / Plastifikatoriaus poveikis sukietėjusio betono savybėms

Mokslas: Lietuvos Ateitis, 2012
Concrete is material obtained mixing matrix material, coarse and small aggregates and water along with additives acquiring necessary properties of hardening.
Anastasija Abasova, Džigita Nagrockienė   +1 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Effects of Modification Methods on Structure and Physicochemical Properties of Insoluble Dietary Fiber in Oat Bran

Shipin gongye ke-ji
This study investigated the effects of snailase (SE), cold plasma (CP), and the combined treatment of snailase and cold plasma (SE-CP) on the structure and physicochemical properties of insoluble dietary fiber (IDF) from oat bran.
Wenting YU, Shu ZHANG, Tianxin FU, Changyuan WANG   +3 more
doaj   +1 more source