Results 61 to 70 of about 201,361 (344)
Moderate structural realism about space-time [PDF]
, 2018 This paper sets out a moderate version of metaphysical structural realism that stands in contrast to both the epistemic structural realism of Worrall and the—radical—ontic structural realism of French and Ladyman. According to moderate structural realism,
Esfeld, Michael, Lam, Vincent
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Defensive realism and the Concert of Europe [PDF]
, 2006 Why do great powers expand? Offensive realist John Mearsheimer claims that states wage an eternal struggle for power, and that those strong enough to seek regional hegemony nearly always do.
Rendall, Matthew
core +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Is There a Compelling Argument for Ontic Structural Realism? [PDF]
, 2011 Structural realism first emerged as an epistemological thesis aimed to avoid the so-called pessimistic meta-induction on the history of science. Some authors, however, suggested that the preservation of structure across theory-change is best explained by
Morganti, Matteo
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Generalism and the Metaphysics of Ontic Structural Realism [PDF]
, 2017 Ontic structural realism (OSR) claims that all there is to the world is structure. But how can this slogan be turned into a worked-out metaphysics? Here I consider one potential answer: a metaphysical framework known as generalism (Dasgupta, 2009, 2016).
Glick, David
core +1 more source
The World Is Either Digital or Analogue [PDF]
, 2014 Peer ...
Berto, Francesco, Tagliabue, Jacopo
core +3 more sources
Is Structural Realism Possible?
Philosophy of Science, 2001 This paper examines in detail two paths that lead to Structural Realism (SR), viz. a substantive philosophical position which asserts that only the structure of the world is knowable. The upward path is any attempt to begin with empiricist premises and reach a sustainable realist position.
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source