Results 91 to 100 of about 3,676,467 (289)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Learning Strict Nash Equilibria through Reinforcement [PDF]

open access: yes
This paper studies the analytical properties of the reinforcement learning model proposed in Erev and Roth (1998), also termed cumulative reinforcement learning in Laslier et al (2001).
Ianni, Antonella
core  

Evaluation method for stochasticity in seismic response of 3D sedimentary basins based on artificial neural network

open access: yesYantu gongcheng xuebao
The scattering of seismic waves by sedimentary basins leads to basin amplification effects and increases earthquake damage of structures. The geotechnical parameters of the basins generally have significantly stochastic characteristics, resulting in the ...
LIU Zhongxian 1, MENG Sibo 2, LI Wenxuan 3, ZHAO Jiawei 3, HUANG Zhenen 4
doaj   +1 more source

Long-Fiber Embedded Hydrogel 3D Printing for Structural Reinforcement. [PDF]

open access: yesACS Biomater Sci Eng, 2022
Sun W   +4 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

考虑建筑群-沉积盆地动力相互作用的建筑群震害评估方法

open access: yesDizhen xuebao
我国大量城镇位于沉积盆地,沉积盆地对地震动具有显著的幅值放大和持时增长效应,同时沉积盆地与建筑群间的动力相互作用将导致地震动空间重分布。针对此问题,本文提出了一种考虑建筑群-沉积盆地动力相互作用的建筑群震害评估方法:首先,以剪切层模型、弯剪耦合模型等简化力学模型模拟建筑结构,计算建筑群-沉积盆地动力相互作用,获得建筑群的基础顶面地震动;然后,基于精细化有限元模型分析典型单体建筑的地震易损性;最后,结合所求建筑群基础顶面地震动、易损性曲线进行建筑群震害评估。结果表明:采用简化力学模型 ...
Zhongxian Liu   +4 more
doaj   +1 more source

Strengthening of the Timber Members Using Fibre Reinforced Polymer Composites [PDF]

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2004
The reinforcement of structural wood products has become in the last decades an efficient method of improving structural capabilities of load carrying members made of this material. Some important steps in earlier stages of research were focused on using
Ioana-Sorina Enţuc   +2 more
doaj  

Mechanical and Permeability Characteristics of Latex-Modified Fiber-Reinforced Roller-Compacted Rapid-Hardening-Cement Concrete for Pavement Repair

open access: yesApplied Sciences, 2017
This study evaluated the effects of reinforcement fibers on the mechanical characteristics, chloride ion penetration properties and abrasion resistance of roller-compacted latex-modified fiber-reinforced rapid-hardening-cement concrete (RCLMFRRHCC) for ...
Seung-Kee Lee   +3 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

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