Results 81 to 90 of about 3,676,467 (289)
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjectiveIn response to the high incidence of loosening defects in key connecting parts in OCS （overhead catenary system） under high-frequency metro operations，the principles，applicability，and effectiveness of various anti-loosening technologies are ...
Qiang XU
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Cutout shape and reinforcement design for composite C-section beams under shear load [PDF]
, 2009 This paper reports a study of the performance of two forms of cutout and various edge reinforcements in a composite C-section beam under static shear load. Firstly, cutout shape effect on stress concentration was studied.
Guo, Shijun J. +3 more
core +1 more source
FEM performance of concrete beams reinforced by carbon fiber bars
MATEC Web of Conferences, 2018 Concrete structures may be vulnerable to harsh environment, reinforcement with Fiber Reinforced Polymer (FRP) bars have an increasing acceptance than normal steel.
Hasan Hashim
doaj +1 more source
Study on Frost Resistance and Interface Bonding Performance through the Integration of Recycled Brick Powder in Ultra-High-Performance Concrete for Structural Reinforcement. [PDF]
Materials (Basel), 2023 Zhang Y +5 more
europepmc +1 more source
Structural design through reinforcement learning
Engineering Applications of Artificial IntelligenceThis paper introduces the Structural Optimization gym (SOgym), a novel open-source Reinforcement Learning (RL) environment designed to advance machine learning in Topology Optimization (TO). SOgym enables RL agents to generate physically viable and structurally robust designs by integrating the physics of TO into the reward function.
Thomas Rochefort-Beaudoin +3 more
openaire +4 more sources