Results 41 to 50 of about 1,367,188 (309)

Cathodic protection of steel in concrete – experience and overview of 30 years application

MATEC Web of Conferences, 2018
This paper presents an overview of 30 years' experience with cathodic protection of steel in concrete in The Netherlands. Principles and practical aspects of CP and its design and installation are presented.
Polder Rob, Peelen Willy
doaj   +1 more source

Effect of the Length of Traffic Flow Records on the Estimate of a Bridge Service Life

Transactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2016
The service life of bridges is significantly affected by fatigue of used material induced by heavy vehicles. Therefore, precise determination of the vehicle weight is of crucial importance for the calculation of fatigue damage and the prediction of the ...
Krejsa Jan, Sykora Miroslav
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Maintenance Optimization of Industrial Chimneys Exposed to Carbonation

Transactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2017
The paper is focused on the deterioration of industrial reinforced concrete chimneys caused by carbonation. It is considered that a chimney has to be repaired when more than 30% of its surface is affected by visible corrosion-induced cracks.
Mlčoch Jan, Marková Jana, Sýkora Miroslav   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Structural durability assessment of welded offshore K-nodes by different local design concepts

Fracture and Structural Integrity, 2009
The structural durability design of complex welded structures should not rely only on one single design method but should apply different methods for assuring the reliability of the assessment.
C. M. Sonsino
doaj   +3 more sources

Updating Material Factors for Assessment of Historic Reinforced Concrete Bridge

Transactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2016
This paper is focused on the reliability analysis of an existing reinforced concrete bridge from 1908. The load bearing capacity is assessed in accordance with valid standards using updated partial factors and the partial factors for structural design ...
Krejsa Jan, Sýkora Miroslav
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Bird strike resistance of a CFRP morphing leading edge

Composites Part C: Open Access, 2021
The implementation of morphing technologies into the leading edge a regional aircraft wing promises some benefits in terms of reduction of perceived noise on the ground as well as reduction of fuel consumption.
Michael May, Sonja Arnold-Keifer, Volker Landersheim, Dominik Laveuve, Conchin Contell Asins, Mathieu Imbert   +5 more
doaj   +1 more source

Reliability approach for safe designing on a locking system [PDF]

, 2010
The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe, DAU, Frédéric, GUILLAUMAT, Laurent, MEALIER, Nicolas   +3 more
core   +3 more sources