Results 71 to 80 of about 4,850,254 (305)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Optimum reliability and structure in reliability-based structural design
, 1978 Od Vol. 43, issue 1 (1991) wyd.: Polish Scientific Publishers = PWN ; Od Vol. 50, issue 4 (1998) wyd.: Agencja Reklamowo-Wydawnicza A. Grzegorczyk ; Od Vol. 53, issue 4/5 (2001) wyd: PAS. IFTR ; 225-332 pages ; 24 cm ; Od Vol. 43, issue 1 (1991) wyd.: Polish Scientific Publishers = PWN ; Od Vol.
Yonezawa, M. +3 more
openaire +1 more source
, 2018 To assess the reliability of a structure, reliability based codes such as EN1990:2002 allow for the application of full-probabilistic methods and semi-probabilistic methods (i.e. the partial factor method). In principle, both methods should be equivalent
Steenbergen, R.D.J.M., Meinen, N.E.
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Estimating Design Resistance of Wrought Balcony Girders
Transactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2017 The contribution is focused on reliability of balcony girders of a Czech national heritage monument. As preliminary reliability assessment suggests insufficient resistance, a series of nondestructive tests supplemented by a single tensile test are ...
Jung Karel +2 more
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Uncertainty in Loading and Control of an Active Column Critical to Buckling
Shock and Vibration, 2012 Buckling of load-carrying column structures is an important design constraint in light-weight structures as it may result in the collapse of an entire structure.
G.C. Enss, R. Platz, H. Hanselka
doaj +1 more source
Reliability of a probabilistic knowledge structure
Behavior Research MethodsAbstractIndexes for estimating the overall reliability of a test in the framework of knowledge space theory (KST) are proposed and analyzed. First, the possibility of applying in KST the existing classical test theory (CTT) methods, based on the ratio between the true score variance and the total variance of the measure, has been explored.
Debora de Chiusole +3 more
openaire +2 more sources
, 2013 It is of great interest to assess during the operation of a dynamic system whether it is expected to satisfy specified performance objectives.To do this, the failure probability (or its complement, robust reliability) of the system when it is subjected
Cheung, Sai Hung, Bansal, Sahil
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source