Results 151 to 160 of about 1,329,617 (295)

Combining pairwise structural similarity and deep learning interface contact prediction to estimate protein complex model accuracy in CASP15. [PDF]

Proteins, 2023
Roy RS, Liu J, Giri N, Guo Z, Cheng J.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Integrated analysis of multimodal single-cell data with structural similarity. [PDF]

Nucleic Acids Res, 2022
Cao Y, Fu L, Wu J, Peng Q, Nie Q, Zhang J, Xie X.   +6 more
europepmc   +1 more source

Similarity assessment of structures for population-based structural health monitoring via graph kernels [PDF]

Chandula T. Wickramarachchi, Julian Gosliga, Andrew Bunce, Daniel S. Brennan, David Hester, Elizabeth J. Cross, Keith Worden   +6 more
openalex   +1 more source

Structural similarity between peanut lectin and concanavalin A [PDF]

, 1987
Srinivasarao Mande, Srinivasan Raghunathan, M. Islam Khan, A. Surolia, M. Vijayan   +4 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Detection of infrared small target based on background subtraction local contrast measure and Gaussian structural similarity. [PDF]

Heliyon, 2023
Zhu D, Tang J, Fu X, Geng Y, Su J.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Annotation of natural product compound families using molecular networking topology and structural similarity fingerprinting. [PDF]

Nat Commun, 2023
Morehouse NJ, Clark TN, McMann EJ, van Santen JA, Haeckl FPJ, Gray CA, Linington RG.   +6 more
europepmc   +1 more source