Results 221 to 230 of about 510,563 (307)

Foldclass and Merizo-search: scalable structural similarity search for single- and multi-domain proteins using geometric learning. [PDF]

Bioinformatics
Kandathil SM, Lau AM, Buchan DWA, Jones DT.   +3 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Structural Similarity, Activity, and Toxicity of Mycotoxins: Combining Insights from Unsupervised and Supervised Machine Learning Algorithms. [PDF]

J Agric Food Chem
Cova TF, Ferreira C, Nunes SCC, Pais AACC.   +3 more
europepmc   +1 more source

Structural Similarity Loss for Learning to Fuse Multi-Focus Images. [PDF]

Sensors (Basel), 2020
Yan X, Gilani SZ, Qin H, Mian A.
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Improving Image Segmentation with Contextual and Structural Similarity. [PDF]

Pattern Recognit
Chen X, Liu Q, Deng HH, Kuang T, Lin HH, Xiao D, Gateno J, Xia JJ, Yap PT.   +8 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Functional domain annotation by structural similarity. [PDF]

NAR Genom Bioinform
Borujeni PM, Salavati R, Salavati R.
europepmc   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

A Convolutional Neural Network with Multifrequency and Structural Similarity Loss Functions for Electromagnetic Imaging. [PDF]

Sensors (Basel)
Chiu CC, Lin CY, Chi YJ, Hsu HH, Chen PH, Jiang H.   +5 more
europepmc   +1 more source