Results 81 to 90 of about 1,329,617 (295)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Labour Market Institutions and Structural Reforms: A Source for Business Cycle Synchronisation? [PDF]

open access: yes
We focus on the influence of institutional variables on business cycle synchronisation for 20 OECD countries from 1979 to 2003. More precisely, this paper derives measures for similarity of institutions and structural reforms, and investigates direct and
Sachs, Andreas, Schleer, Frauke
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Statistical Difference Representation-Based Transformer for Heterogeneous Change Detection

open access: yesSensors
Heterogeneous change detection refers to using image data from different sensors or modalities to detect change information in the same region by comparing images of the same region at different time periods.
Xinhui Cao   +4 more
doaj   +1 more source

Optimal structural similarity constraint for reversible data hiding

open access: yes网络与信息安全学报, 2016
Most reversible data hiding (RDH) techniques have been evaluated by PSNR,which is based on MSE.Unfortunately,MSE turns out to be an extremely poor measure when the purpose is to predict perceived signal fidel-ity or quality.The structural similarity ...
Jia-jia XU,Wei-ming ZHANG,Rui-qi JIANG,Neng-hai YU,Xiao-cheng HU
doaj   +1 more source

Determinant factors of structural similarity at the regional level: evidence from Portugal [PDF]

open access: yes
There is scant evidence on the determinant factors of structural similarity between geographical spaces; moreover, it has been produced considering only the national level. The present study provides evidence on this topic at the regional level, based on
Maria Paula Fontoura, Nuno Crespo
core  

Integrating Segmentation and Similarity in Melodic Analysis [PDF]

open access: yes, 2002
The recognition of melodic structure depends on both the segmentation into structural units, the melodic motifs, and relations of motifs which are mainly determined by similarity.
Weyde, T.
core   +1 more source

Convex Relaxations for Permutation Problems

open access: yes, 2015
Seriation seeks to reconstruct a linear order between variables using unsorted, pairwise similarity information. It has direct applications in archeology and shotgun gene sequencing for example.
Bach, Francis   +3 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Unsupervised segmentation of mitochondria using model-based spectral clustering [PDF]

open access: yes, 2013
Segmentation of mitochondria in microscopic images represents a significant challenge that is motivated by the wide morphological and structural variations that are characteristic for this category of membrane enclosed sub cellular organelles. To address
Dietlmeier, Julia   +2 more
core   +1 more source

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