Results 71 to 80 of about 770,807 (317)

State and trait characteristics of anterior insula time-varying functional connectivity. [PDF]

open access: yes, 2020
The human anterior insula (aINS) is a topographically organized brain region, in which ventral portions contribute to socio-emotional function through limbic and autonomic connections, whereas the dorsal aINS contributes to cognitive processes through ...
Allen, Isabel   +18 more
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Implementation of the Structural SIMilarity (SSIM) Index as a Quantitative Evaluation Tool for Dose Distribution Error Detection.

open access: yesMedical Physics (Lancaster), 2020
PURPOSE To apply an imaging metric of the Structural SIMilarity (SSIM) index to the radiotherapy dose verification field and evaluate its capability to reveal the different types of errors between two dose distributions.
Jiayuan Peng   +6 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Error Sensitivity Analysis of DMB Transport Streams

open access: yesIEEE Access, 2019
In this paper, we examine the sensitivity of the digital multimedia broadcasting (DMB) MPEG-2 transport stream (TS) format to transmission errors. To find the sensitivity of different parts of TS packets to transmission errors, each TS packet is divided ...
Muhammad Imran Iqbal   +1 more
doaj   +1 more source

Adversarial Learning of Semantic Relevance in Text to Image Synthesis

open access: yes, 2019
We describe a new approach that improves the training of generative adversarial nets (GANs) for synthesizing diverse images from a text input. Our approach is based on the conditional version of GANs and expands on previous work leveraging an auxiliary ...
Cha, Miriam   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Joint inversion of gravity and vertical gradient data based on modified structural similarity index for the structural and petrophysical consistency constraint

open access: yesGeodesy and Geodynamics, 2023
Joint inversion is one of the most effective methods for reducing non-uniqueness for geophysical inversion. The current joint inversion methods can be divided into the structural consistency constraint and petrophysical consistency constraint methods ...
Sheng Liu   +8 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Linear Regression Supporting Vector Machine and Hybrid LOG Filter-Based Image Restoration

open access: yesJournal of Intelligent Systems, 2019
The image restoration (IR) technique is a part of image processing to improve the quality of an image that is affected by noise and blur. Thus, IR is required to attain a better quality of image.
Basha D. Khalandar, Venkateswarlu T.
doaj   +1 more source

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