Results 91 to 100 of about 7,449,096 (281)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Incorporation of Structural Similarity Index and Regularization Term into Neighbor2Neighbor Unsupervised Learning Model for Efficient Ultrasound Image Data Denoising

Applied Sciences
Medical ultrasound imaging is extensively employed for diagnostic purposes. However, image quality remains a major obstacle to achieving greater accuracy.
Peiyang Wei, Liping Wang, Jianhong Gan, Xiaoyu Shi, Mingsheng Shang   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Measuring export similarity in the ASEAN agricultural sector: Evidence from Indonesia’s agrifood and non-agrifood trade [PDF]

BIO Web of Conferences
Agricultural trade remains a crucial pillar of ASEAN's economic cooperation, yet the region still faces challenges in aligning its export structures across member countries.
Danendra Daffa Ibra, Novianti Tanti, Hidayat Nia Kurniawati   +2 more
doaj   +1 more source

Comparison between Structural Similarity Index Metric and Human Perception [PDF]

, 2011
This thesis examines the image quality assessment using Structural Similarity Index Metric (SSIM). The performance of Structural Similarity Index Metric was evaluated by comparing Mean Structural Similarity Index (MSSIM) index values with the Probability
Chilakamarthi, Tanmayi
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Flare Removal Model Based on Sparse-UFormer Networks

Entropy
When a camera lens is directly faced with a strong light source, image flare commonly occurs, significantly reducing the clarity and texture of the photo and interfering with image processing tasks that rely on visual sensors, such as image segmentation ...
Siqi Wu, Fei Liu, Yu Bai, Houzeng Han, Jian Wang, Ning Zhang   +5 more
doaj   +1 more source

Structural identifiability analysis via symmetries of differential equations [PDF]

, 2009
Results and derivations are presented for the generation of a local Lie algebra that represents the 'symmetries' of a set of coupled differential equations.
Yates, James W. T., Chappell, M. J. (Michael J.), Evans, Neil D.   +2 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source