Results 81 to 90 of about 7,449,096 (281)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Classification of Abdominal CT Images bearing Liver Tumor Using Structural Similarity Index and Support Vector Machine

Mehran University Research Journal of Engineering and Technology, 2020
Computed Tomographic (CT) imaging is extensively implemented for liver tumor visualization and detection. Computer aided image processing algorithms can provide aid to the physicians and radiologists in detecting deadly diseases of liver specifically ...
Ayesha Amir Siddiqi, Attaullah Khawaja, Adnan Hashmi   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Consensus between pipelines in structural brain networks. [PDF]

, 2014
Structural brain networks may be reconstructed from diffusion MRI tractography data and have great potential to further our understanding of the topological organisation of brain structure in health and disease.
Dayan, M, Fani Deligianni, Clayden, Jonathan, Daga, Pankaj (5302726), Clayden, JD, Jonathan D. Clayden (388576), Parker, CS, Cardoso, M., M Jorge Cardoso, Modat, M, Fani Deligianni (651913), Pankaj Daga (3705391), Clark, CA, Jonathan D Clayden, Michael Dayan, Chris A Clark, Clayden, Jonathan D. (5302705), Cardoso, MJ, Parker, Christopher S. (5302711), Daga, Pankaj, Dayan, Michael, Clark, Chris, Daga, P, Deligianni, Fani (5302729), Clark, Chris A., Modat, Marc (5302723), Chris A. Clark (388579), Parker, Christopher S., Ourselin, Sebastien, Modat, Marc, Pankaj Daga, Michael Dayan (405211), Ourselin, Sebastien (5302708), Clark, Chris A. (5302714), Sebastien Ourselin (300144), Cardoso, M. Jorge (5302720), Christopher S. Parker (651912), Parker, Christopher, Christopher S Parker, Clayden, Jonathan D., M. Jorge Cardoso (390129), Sebastien Ourselin, Ourselin, S, Marc Modat (300140), Deligianni, F, Deligianni, Fani, Cardoso, M. Jorge, Marc Modat, Dayan, Michael (5302717)   +48 more
core   +1 more source

Robust Registration of Multispectral Satellite Images Based on Structural and Geometrical Similarity

, 2021
Accurate registration of multispectral satellite images is a challenging task due to the significant and nonlinear radiometric differences between these data.
Li, J, Chi, Q, Lv, G, Awrangjeb, M
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Pharmacogenomic Drug–Target Network Analysis Reveals Similarity Profiles Among FDA–Approved Cancer Drugs

Pharmaceutics
Background: Defining specific molecular targets for cancer therapeutics remains a significant challenge in oncology. Many Food and Drug Administration (FDA)-approved anticancer drugs have incomplete target profiles, which limits our understanding of ...
Alberto Berral-González, Monica M. Arroyo, Diego Alonso-López, María Jesús Rivas-López, José Manuel Sánchez-Santos, Javier De Las Rivas   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Constructing Ghost Free High Dynamic Range Images Using Convolutional Neural Network And Structural Similarity Index

JISR on Computing, 2017
A foreign object, commonly called as a ghost artifact, is integrated in the HDR output image when there is a moving object in the photography scene. The problem is persisting even after numerous models proposed by researchers.
Shahid Khan, Husnain Mansoor Ali
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source