Results 101 to 110 of about 130,939 (282)

Document Image Retrieval Based on Layout Structural Similarity [PDF]

, 2008
—In this paper, we describe issues related to the measurement of structural similarity between document images. We define structural similarity, and discuss the benefits of using it as a complement to content similarity for querying document image ...
Christian Shin, David Doermann
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Compressed materialised views of semi-structured data [PDF]

, 2007
Query performance issues over semi-structured data have led to the emergence of materialised XML views as a means of restricting the data structure processed by a query.
Gourlay, Richard, Brian Tripney, John Wilson, Tripney, B., Wilson, John, Gourlay, R., Richard Gourlay, Tripney, Brian, Wilson, J.   +8 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Search Efficiency in Indexing Structures for Similarity Searching

CoRR, 2004
Similarity searching finds application in a wide variety of domains including multilingual databases, computational biology, pattern recognition and text retrieval. Similarity is measured in terms of a distance function, edit distance, in general metric spaces, which is expensive to compute. Indexing techniques can be used reduce the number of distance
Girish Motwani, Sandhya G. Nair
openaire   +2 more sources

APPLICATION OF STRUCTURAL SIMILARITY INDEX FOR ANALYSIS OF X-RAY IMAGES OF INSPECTION-INSPECTION COMPLEXES OF CUSTOMS CONTROL [PDF]

This article discusses a method for analyzing X-ray images obtained using Inspection and Examination Complexes using digital transformation algorithms. The relevance of the topic is due to the need to increase the efficiency of control over the transit ...
Tojimatov, S.K., Dusmukhamedov, A.I., Saidov, A.A.   +2 more
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Fused Image Quality Measure Based on Structural Similarity [PDF]

, 2011
Under the assumption that human visual perception is highly adapted for extracting structural information from a scene, we present a new approach using structural similarity index for assessing quality in image fusion.
Ben Kang Chang, Jun Ju Zhang, Yi Hui Yuan, Hui Xu, Yi Yong Han   +4 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source