Results 121 to 130 of about 7,449,096 (281)
High and low similarity backbone extraction using similarity-based link prediction
Applied Network ScienceComplex networks are fundamental to understanding systems across diverse domains. However, their increasing size and complexity pose challenges for analysis and scalability.
Ali Yassin +3 more
doaj +1 more source
Big Data and Cognitive ComputingTraditional image denoising algorithms often struggle with real-world complexities such as spatially correlated noise, varying illumination conditions, sensor-specific noise patterns, motion blur, and structural distortions.
Ismail Boucherit, Hamza Kheddar
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Structural similarity of lithospheric velocity models of Chinese mainlandKey points
Earthquake ScienceExisting lithospheric velocity models exhibit similar structures typically associated with the first-order tectonic features, with dissimilarities due to different data and methods used in model generation.
Feng Huang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
, 2013 MartiTracks calculates the similarity among tracks through a similarity index (SI). Given two tracks , (either individual, or generalized tracks), the similarity index is the length of the congruent segments from to divided by the total length of the
Susy Echeverría-Londoño (353489) +1 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
The High-Resolution Rate-Distortion Function under the Structural Similarity Index
EURASIP Journal on Advances in Signal Processing, 2011 Jan Østergaard +2 more
doaj +1 more source