Results 81 to 90 of about 770,807 (317)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Gamma norm minimization based image denoising algorithm

Tongxin xuebao, 2020
Focusing on the issue of rather poor denoising performance of the traditional kernel norm minimization based method caused by the biased approximation of kernel norm to rank function,based on the low-rank theory,a gamma norm minimization based image ...
Hongyan WANG, Tuo WANG, Mian PAN, Zumin WANG   +3 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Assessment of the Image Quality of Virtual Non-Contrast Dual-energy CT Liver Scans Using Both PSNR and SSIM Methods

CT Lilun yu yingyong yanjiu
The purpose of this study was to investigate the feasibility of replacing true non-contrast (TNC) dual-energy computed tomography (DECT) images with virtual non-contrast (VNC) DECT images by comparing their quality on the basis of both the peak signal-to-
Yaguang LI, Jie LI, Tingyu XUE, Jiankui MU, Qiang WANG, Lidong ZHENG, Yong WANG, Licun LEI   +7 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Competition in Tourism Arrivals: A Multidimensional Index of Geographical Structural Similarity [PDF]

Tourism Analysis, 2016
Given the economic importance of the tourism sector, countries actively compete for attracting tourism flows. In a bilateral perspective, an important determinant of the degree of competition is the geographical structure of tourism inflows (i.e., the relative importance of the different source countries).
Nuno Crespo, Nádia Simões, José Duarte   +2 more
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

An improved nonlocal sparse regularization-based image deblurring via novel similarity criteria

International Journal of Advanced Robotic Systems, 2018
Image deblurring is a challenging problem in image processing, which aims to reconstruct an original high-quality image from its blurred measurement caused by various factors, for example, imperfect focusing caused by the imaging system or different ...
Nannan Wang, Wenxuan Shi, Ci’en Fan, Lian Zou   +3 more
doaj   +1 more source

Classification of Abdominal CT Images bearing Liver Tumor Using Structural Similarity Index and Support Vector Machine

Mehran University Research Journal of Engineering and Technology, 2020
Computed Tomographic (CT) imaging is extensively implemented for liver tumor visualization and detection. Computer aided image processing algorithms can provide aid to the physicians and radiologists in detecting deadly diseases of liver specifically ...
Ayesha Amir Siddiqi, Attaullah Khawaja, Adnan Hashmi   +2 more
doaj   +1 more source