Results 151 to 160 of about 1,028,024 (317)

Reconfigurable architected material systems inspired by feather shaft mechanics

npj Metamaterials
Shape memory behavior in engineered systems is traditionally achieved through material-level phase transformations or polymer network rearrangements.
Phani Saketh Dasika, Yunlan Zhang, Somayajulu Dhulipala, Lei Wu, Carlos M. Portela, Pablo D. Zavattieri   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Numerical Determination of the Load-Bearing Capacity of a Perforated Thin-Walled Beam in a Structural System with a Steel Grating

Applied Sciences
This article presents the results of numerical simulations of a structural system consisting of steel perforated thin-walled beams and a steel grating. The simulations were conducted using the finite element method.
Arkadiusz Denisiewicz, Tomasz Socha, Krzysztof Kula, Wojciech Macek, Wojciech Błażejewski, Grzegorz Lesiuk   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Projeto de sistemas ótimos de obsorsores viscoelásticos de vibração através de uma função objetivo baseada na norma matricial de Frobenius [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Mecânica.Neutralizadores dinâmicos de vibrações são subsistemas mecânicos (em geral, sistemas com um grau de liberdade) que, anexados ao ...
Pereira, Petroneo
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Structural parameters optimization for enhanced sealing performance of soluble ball seat sealing ring in shale gas volume fracturing process.

PLoS ONE
In the volumetric fracturing process of tight oil and gas horizontal wells, the soluble ball seat emerges as a crucial tool for pressure sealing due to its rapid solubility, full-diameter production capacity, and straightforward construction process ...
Shuang Jing, Anle Mu, Zhen Chen, Qingjie Ran, Deyong Luo, Tao Xiong   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source