Results 201 to 210 of about 3,753,947 (257)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi   +6 more
wiley   +1 more source

Left atrial function in uraemic patients: Four‐dimensional automatic left atrial quantitative technology study

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1316-1325, April 2025.
Abstract Objective This study aimed to evaluate the utility of left atrial volume and function in uraemic patients using four‐dimensional automatic left atrial quantification (4D auto LAQ) technology. Methods Thirty‐four undialysed uraemic patients (U‐ND group), 60 dialysed uraemic patients (U‐D group), and 32 healthy volunteers (N group) were enrolled
Bing Li, Meihua Chen, Xuning Huang
wiley   +1 more source

Structural Valve Deterioration in Surgical Versus Transcatheter Aortic Valve Replacement

open access: yesJournal of the American College of Cardiology, 2019
Gilbert H.L. Tang   +2 more
openaire   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner   +15 more
wiley   +1 more source

Genetic Algorithm‐Driven Analysis of Gravitational Water Vortex Power Plant Runner Performance: A Comparative Study Integrating Experimental and Computational Fluid Dynamics

open access: yesEnergy Science &Engineering, EarlyView.
This study integrates genetic algorithm optimization, CFD simulation, and experimental validation to identify the optimal runner geometry for a gravitational water vortex turbine. The combined approach enhances vortex stability and improves energy conversion efficiency, demonstrating strong agreement between predicted and measured performance ...
Zakaria. A. Mwakitwange, Adam Faraji
wiley   +1 more source

Pulsed wave tissue Doppler imaging of the left ventricle in foals: Feasibility, inter‐ and intra‐observer variability and wave pattern over the first days of life

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Tissue Doppler imaging (TDI) may improve the assessment of myocardial function in neonatal foals. Objectives To document the feasibility of left ventricular pulsed wave (PW) TDI, inter‐ and intra‐observer variability and wave pattern over the first 5 days of life. Study Design Prospective observational study.
Fernanda Timbó D'el Rey Dantas   +8 more
wiley   +1 more source

A Case of TAV-in-SAV in a Patient with Structural Valve Deterioration after Surgical Aortic Valve Replacement with the INSPIRIS RESILIA Valve. [PDF]

open access: yesAnn Thorac Cardiovasc Surg
Matsuda M   +6 more
europepmc   +1 more source

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

open access: yesExploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang   +9 more
wiley   +1 more source

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