Results 101 to 110 of about 4,271,392 (311)
Evaluation of association of HNF1B variants with diverse cancers : collaborative analysis of data from 19 genome-wide association studies [PDF]
, 2010 Background
Genome-wide association studies have found type 2 diabetes-associated variants in the HNF1B gene to exhibit reciprocal associations with prostate cancer risk.Tomlinson, IP, Mann, GJ, Hwang, Shih-Jen, Hopper, John L., Hwang, SJ, Amos, CI, Barkardottir, Rosa B., McCarthy, Mark I, Carvajal-Carmona Luis, Albanes, D, Xu, J, Armstrong, Bruce K., Kenneth Muir, Stefansson Kari, Jacobs, EJ, Amos Christopher I., Zanke, B, Barkardottir, Rosa B, Jenab, M, Michaud, DS, Xu Jianfeng, Mendelsohn, JB, Muir, K, Hamdy, Freddie C., Stolzenberg-Solomon, RZ, Aitken, JF, Mathieu Lemire, Aitken, Joanne F., John P. A. Ioannidis, null null, Hunter, David, Hallmans, G, Donovan, Jenny L, Murabito Joanne M., Risch, HA, Hamdy, FC, Rafnar Thorunn, Giles, Graham G., Donovan, JL, Tomlinson, Ian P. M., Hunter David J., Margaret R Spitz, Macgregor, Stuart, Tomlinson Ian P. M., Spitz, Margaret R., Hopper, JL, David E. Neal, Duell, EJ, Stefansson, K, Simon N Stacey, Gudbjartsson, Daniel F, Julius Gudmundsson, David J Hunter, Armstrong, BK, Neal David E., Easton Douglas F., Amundadottir, L, Kari Stefansson, Stephen J Chanock, Hayward Nicholas K., Zeggini, E, Neal, David E, Isaacs, William B, Easton, DF, Chanock, Stephen J, Patel, AV, Douglas F. Easton, Brown Kevin M., Petersen, GM, Thorlacius, Steinunn, Isaacs, William B., William B Isaacs, Gallinger, S, Klein, AP, Gaborieau Valerie, Donovan, Jenny, Kraft, P, Kevin M Brown, Giovannucci, EL, Holly, EA, Lemire, Mathieu, Rosa B. Barkardottir, Sulem, P, Barkardottir, RB, Neal, David E., Zeggini, Eleftheria, Valerie Gaborieau, Chanock, Stephen J., Kevin M. Brown, Zeggini Eleftheria, Barkardottir, Rosa, HASH(0x55a67fc6f008), Riboli, E, Hayward, NK, Shu, XO, Howard, B, David E Neal, Stacey, Simon N., Gronberg, H, PanScan, C, Parikh, H, Gudmundsson Julius, Hassan, M, Ian P. M. Tomlinson, Tomlinson, IPM, Ioannidis, JPA, Gudmundsson, Julius, Carvajal-Carmona, Luis, McCarthy, MI, Kefford, Richard F., Clipp, S, McCarthy Mark I., Donovan Jenny L., Brent Zanke, Muir, Kenneth, Neal, DE, Ioannidis, John P., Li, D, Amundadottir Laufey, Canzian, F, Eeles, RA, Rodriguez, L, Gudmundsson, J, Mark I. McCarthy, Xu, Jianfeng, Elliott, Katherine S, Hutchinson, A, Krogh, V, Mann, Graham J., Thomas, G, Ioannidis, John PA, Eeles Rosalind A., Brown, Kevin M., Stacey, SN, Ioannidis, John, Kefford, RF, Sulem, Patrick, Katherine S Elliott, Gudbjartsson Daniel F., Murabito, JM, Stacey Simon N., McCarthy, Mark I., Gudbjartsson, DF, Hamdy Freddie C., Jenny L. Donovan, Eleftheria Zeggini, Hunter, David J., Luis Carvajal-Carmona, Chanock, Stephen, Hayward, Nicholas K., Michael Gaziano, J, Hunter, David J, Shih-Jen Hwang, Jianfeng Xu, The PanScan Consortium, Buring, JE, Amos, Christopher I, Henrik Grönberg, PanScan Consortium, Giles, GG, Rafnar, Thorunn, Easton, Douglas F, Nicholas K. Hayward, Brown, KM, Chanock Stephen J., Jenny L Donovan, Rosalind A Eeles, Arslan, AA, Seminara, D, Goggins, M, Stefansson, Kari, Murabito, Joanne M., Hunter, DJ, McCarthy, Mark, Tomlinson, Ian PM, Donovan, Jenny L., Rajkovic, A, Zanke Brent, Hamdy, Freddie C, Nicholas K Hayward, Thorlacius Steinunn, Hayward, Nicholas K, Joanne M. Murabito, Lynch, SM, Isaacs William B., Daniel F. Gudbjartsson, Elliott, Katherine S., Ioannidis, John P. A., Fuchs, CS, de Andrade, M, Hankinson, SE, Grönberg Henrik, Lemire Mathieu, Christopher I. Amos, Gross, M, Mandelson, MT, Spitz, Margaret R, Ioannidis, John P.A., Helzlsouer, K, Laufey Amundadottir, Bracci, PM, Tomlinson, Ian, Kooperberg, C, Kurtz, RC, Grönberg, H, John P A Ioannidis, Sulem Patrick, Eeles, Rosalind A, McWilliams, RR, Gaborieau, V, Elliott Katherine S., Ioannidis, JP, Christopher I Amos, Tjønneland, A, Stuart Macgregor, Rosalind A. Eeles, Berg, CD, Rosa B Barkardottir, Joanne M Murabito, Isaacs, WB, Elliott, KS, Bamlet, WR, Freddie C. Hamdy, Macgregor, S, Freddie C Hamdy, Grönberg, Henrik, Carvajal-Carmona, L, Gaborieau, Valerie, Easton, Douglas F., Lemire, M, Rafnar, T, Simon N. Stacey, Olson, SH, Amundadottir, Laufey, Chanock, SJ, Cotterchio, M, Muir Kenneth, Stephen J. Chanock, Australian Melanoma Family Study Investigators, Ioannidis John P. A., Margaret R. Spitz, Thorlacius, S, Stacey, Simon N, Tomlinson, Ian P M, Spitz Margaret R., Ioannidis, John P A, Brennan Paul, Steinunn Thorlacius, Mark I McCarthy, Lacroix, A, Paul Brennan, David J. Hunter, Patrick Sulem, William B. Isaacs, Brennan, P, Hwang Shih-Jen, Brown, Kevin M, Douglas F Easton, Daniel F Gudbjartsson, Zheng, W, Katherine S. Elliott, Gudbjartsson, Daniel Fannar, Thorunn Rafnar, Bas Bueno-De-Mesquita, H, Hamdy, Freddie, Boutron-Ruault, MC, Gudbjartsson, Daniel F., Tomlinson, Ian P.M., Zanke, Brent, Macgregor Stuart, Barkardottir Rosa B., Amos, Christopher I., Murabito, Joanne M, Jacobs, KB, Australian, MFSI, Brennan, Paul, Peeters, PHM, Spitz, MR, Kaaks, R, Eeles, Rosalind A., Ian P M Tomlinson +280 morecore +1 more sourceGet ready for short tandem repeats analysis using long reads-the challenges and the state of the art
Frontiers in GeneticsShort tandem repeats (STRs) are repetitive DNA sequences that contribute to genetic diversity and play a significant role in disease susceptibility. The human genome contains approximately 1.5 million STR loci, collectively covering around 3% of the ...Marija Chaushevska, Marija Chaushevska, Karmele Alapont-Celaya, Anne Kristine Schack, Anne Kristine Schack, Lukasz Krych, M. Carmen Garrido Navas, M. Carmen Garrido Navas, M. Carmen Garrido Navas, Anastasia Krithara, Gjorgji Madjarov, Gjorgji Madjarov +11 moredoaj +1 more sourceLigand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada +5 morewiley +1 more sourceIdentification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization [PDF]
, 2012 Introduction: In recent genome-wide association studies for psoriatic arthritis (PsA) and psoriasis vulgaris, common coding variants in the TRAF3IP2 gene were identified to contribute to susceptibility to both disease entities.Maria Apel, Böhm, Beate B., Steffen Uebe, Böhm, Beate, Apel, Maria, Behrens, Frank, Harald Burkhardt, Frank Behrens, Burkhardt, Harald, Beate Bohm, Hüffmeier, Ulrike, Ulrike Huffmeier, Reis, André, Uebe, Steffen, Andre Reis +14 morecore +1 more sourceAdvancing crop improvement through GWAS and beyond in mung bean
Frontiers in Plant ScienceAccessing the underlying genetics of complex traits, especially in small grain pulses is an important breeding objective for crop improvement. Genome-wide association studies (GWAS) analyze thousands of genetic variants across several genomes to identify Syed Riaz Ahmed, Muhammad Jawad Asghar, Muhammad Jawad Asghar, Amjad Hameed, Amjad Hameed, Maria Ghaffar, Maria Ghaffar, Muhammad Shahid, Muhammad Shahid +8 moredoaj +1 more sourceCircadian gene variants and susceptibility to type 2 diabetes : a pilot study [PDF]
, 2012 Background
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility.O’Hare J. Paul, Shahrad Taheri (57360), M. Ann Kelly (174447), Shera, A. Samad, Hydrie MZ, Barnett, Anthony H., Taheri, S., Anthony H Barnett, Kumar S, Shera, A.S., Rees, Simon D., Kelly, M. Ann, Kelly, Marilyn, Shera, AS, Raychaudhuri, Soumya, Sudhesh Kumar (89490), Abdul Basit (174463), Bellary, Srikanth, Rees, S.D., Kumar, S., Barnett AH, J Paul O'Hare, M. Zafar I. Hydrie (174450), Basit, A., Bellary Srikanth, O'Hare, JP, Bellary S, Shera, A Samad, Taheri S, DIAGRAM Consortium, Hydrie, MZ, Taheri, Shahrad, M Zafar I Hydrie, Bellary, S., Abdul Basit, Hydrie M. Zafar I., Shera A. Samad, Barnett, Anthony, Bellary, S, Basit Abdul, Basit, A, Rees SD, Kumar Sudhesh, Srikanth Bellary (89487), Rees, Simon D, Sudhesh Kumar, Shahrad Taheri, O'Hare, J Paul, Rees, Simon, Kelly, M Ann, SAT2D Consortium, Hydrie, M.Z.I., Kelly MA, A Samad Shera, Basit, Abdul, Barnett, A.H., Anthony H. Barnett (174467), Rees Simon D., Kelly, M.A., Srikanth Bellary, Shera AS, Basit A, Hydrie, M Zafar I, Hydriem, Zafar L., Kumar, Sudhesh, Barnett, Anthony H, O'Hare, J.P., Kelly M. Ann, Hydrie, M. Zafar I., Simon D Rees, Kumar, S, A. Samad Shera (174452), O'Hare, J. Paul, Taheri Shahrad, Barnett Anthony H., J. Paul O’Hare (174457), M Ann Kelly, Simon D. Rees (174448) +77 morecore +1 more source
