Results 241 to 250 of about 908,392 (296)

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

cuteFC: regenotyping structural variants through an accurate and efficient force-calling method. [PDF]

Genome Biol
Jiang T, Cao S, Liu Y, Zhang Z, Liu B, Luo R, Wang G, Wang Y.   +7 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Benign mosaic chromosomal structural variants across generations: evidence for a developmental correction mechanism from clinical and computational models. [PDF]

Front Genet
Ruan J, Song Q, Hu Y, Liu X, Li S, Zhu J, Yang L.   +6 more
europepmc   +1 more source

Identifying Structural Variants and Their Contribution to Cardiovascular Disease Risk: The Long and the Short of It. [PDF]

J Am Heart Assoc
Chen HH, Stewart AFR.
europepmc   +1 more source

Haptoglobin phenotypes and structural variants associate with post-exertional malaise and cognitive dysfunction in myalgic encephalomyelitis. [PDF]

J Transl Med
Moezzi A, Ushenkina A, Widgren A, Bergquist J, Li P, Xiao W, Rostami-Afshari B, Leveau C, Elremaly W, Caraus I, Franco A, Godbout C, Nepotchatykh O, Moreau A.   +13 more
europepmc   +1 more source

Long-read sequencing reveals that the mitochondrial genome of an individual <i>Ixodiphagus hookeri</i> is a mixture of structural variants with an invariable core region and heterogeneous repeat regions. [PDF]

Curr Res Parasitol Vector Borne Dis
Dirks RP, Jansen HJ, Veneman WJ, Segobola J, Baede VO, Blažeková V, Stanko M, Víchová B, Sprong H.   +8 more
europepmc   +1 more source

Optical genome mapping identifies rare structural variants in neural tube defects. [PDF]

Genome Res
Sahajpal NS, Dean J, Hilton B, Fee T, Skinner C, Hastie A, DuPont BR, Chaubey A, Friez MJ, Stevenson RE.   +9 more
europepmc   +1 more source