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Structural Variant Breakpoint Detection with novoBreak

2018
Structural variations (SVs) are an important type of genomic variants and always play a critical role for cancer development and progression. In the cancer genomics era, detecting structural variations from short sequencing data is still challenging. We developed a novel algorithm, novoBreak (Chong et al. Nat Methods 14:65-67, 2017), which achieved the
Zechen, Chong, Ken, Chen
openaire   +2 more sources

Structural Variants of Human and Murine Immunoglobulins

1975
Much of the current knowledge of immunoglobulin structure and function has been derived from studies of the homogeneous proteins produced by patients with neoplasms of plasma cells and lymphocytes. These proteins are antigenically and chemically closely related to the normal immunoglobulins and there is now little doubt that most of the homogeneous ...
E C, Franklin, B, Frangione
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Time-Variant Robustness of Aging Structures

2014
This chapter presents recent advances in the field of structural robustness and progressive collapse of deteriorating structural systems, with emphasis on the relationships among structural robustness, static indeterminacy, structural redundancy, and failure times.
BIONDINI, FABIO, D. M. Frangopol
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Faster detection of somatic structural variants

Nature Biomedical Engineering, 2023
Zi-Ning Choo, Marcin Imieliński
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Mako: A Graph-Based Pattern Growth Approach to Detect Complex Structural Variants

Genomics, Proteomics and Bioinformatics, 2022
Lin Jiadong   +2 more
exaly  

Genomic structural variants constrain and facilitate adaptation in natural populations of Theobroma cacao , the chocolate tree

Proceedings of the National Academy of Sciences of the United States of America, 2021
Tuomas Hämälä   +2 more
exaly  

Structural Variants

1965
Bernard John, Kenneth R. Lewis
openaire   +1 more source

A New Structural Attack for GPT and Variants

2005
In this paper we look at the Gabidulin version of the McEliece cryptosystem (GPT) and its variants. We propose a new polynomial time attack, which recovers an alternative private key. Our attack is applicable to all variants proposed so far and breaks some of them completely.
openaire   +1 more source

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