Results 91 to 100 of about 87,014 (312)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structuralism as a Stance

open access: yesPhilosophy of Physics
In this paper, I argue that ontic structural realism is best understood not as a thesis or doctrine concerning how the world fundamentally is, but rather as a “stance” in the sense of van Fraassen (2002).
Kerry McKenzie
doaj   +1 more source

Grounds and Structural Realism: A Possible Metaphysical Framework [PDF]

open access: yes, 2017
This article discusses the proposal of accommodating grounding theories and structural realism, with the aim to provide a metaphysical framework for structural realism.
Savu, Bianca-Alexandra
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

La fenomenología como estructuralismo genético natural

open access: yesEnfoques, 2016
A menudo se ha presentado a la fenomenología y al estructuralismo como perspectivas contra puestas. Nos proponemos revisar esta confrontación. Argumentaremos que hubo cierta influencia de Husserl en el estructuralismo de principios del siglo XX, y que ...
Carlos Belvedere
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Creativity, dialogue, and place: Vitebsk, the early Bakhtin and the origins of the Russian avant-garde [PDF]

open access: yes, 2014
This paper attempts to avoid both the ‘Bakhtinology’ that has become the basis of the ‘Bakhtin industry’ in Russia and the Americanization of his work as a “a sort of New Left celebrator of popular culture” (McLemee, 1997) to argue for a radical ...
Peters, Michael A.   +1 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structuralism in Archaeology

open access: yesEtnoantropološki Problemi, 2016
Although, back in the 1970s, Edmund Leach threatened archaeology that he will ‘poison’ it with structuralism, his structuralist work did not have that far reaching impact on the changes of archaeological interpretative paradigms. The reason for that is –
Aleksandar Palavestra
doaj  

How pluralistic is the research field on adult education? Dominating bibliometrical trends, 2005-2012 [PDF]

open access: yes, 2015
What the field of adult education research is and how it can be described has been a debated issue over the decades. Several scholars argue that the field today is heterogeneous, borrowing theories and methods from a range of disciplines. In this article,
Fejes, Andreas, Nylander, Erik
core   +3 more sources

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