Results 101 to 110 of about 87,014 (312)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

La cuarta exclusión. Notas sobre lingüística formal

open access: yesLexis, 2015
Formal linguistics is posible only if a program of three exclusions is put into place: exclusion of reference, diachrony and the Subject. The first one to embrace this program was Saussure and then, the different versions of structuralism followed suite.
Mario Montalbetti
doaj  

The sctructuralismo as epistemology and method

open access: yesRevista de estudios teóricos y epistemológicos en política educativa, 2019
The aim of this article is to illustrate the teachers, researchers, academics and students of the Human and Social Sciences, in a general view, but with distinctive features, about history, some theoretical foundations and some final considerations on ...
Luis Francisco Ochoa Rojas
doaj   +1 more source

STRUCTURAL INTEGRITY OF MATERIALS AND STRUCTURES

open access: yesEngineering Structures and Technologies, 2017
"Editorial.
Correia, José   +2 more
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Greimas’s Semiotics: Between Structuralism and Phenomenology

open access: yesProblemos, 2019
Greimas’s semiotics is characterized by an inner duality. This is the inner tension between structuralism and phenomenology. The aim of the paper is to reveal the relationship between structuralism and phenomenology in semiotics.
Dalius Jonkus
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Legacy of Structuralism: From Its Dogmas to Methodological Pluralism

open access: yesSententiae
There is a widespread idea that the Philosophy Department at University of São Paulo, has been structuralist since the 1960s. In my opinion, this is a myth, the result of a misunderstanding of what structuralism is.
Plínio Junqueira Smith
doaj   +1 more source

Syntax and semantics in the history of Chinese [PDF]

open access: yes, 2010
The philosophy of language comes in three varieties. 1. The functionalist’s view: linguistic forms are instruments used to convey meaningful elements. This is the basis of European structuralism. 2.
Kortlandt, Frederik H. H.
core  

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