Results 81 to 90 of about 20,557 (293)
STRUCTURAL INTEGRITY OF MATERIALS AND STRUCTURES
Engineering Structures and Technologies, 2017 "Editorial.
Correia, José +2 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Etnoantropološki Problemi, 2016 Although, back in the 1970s, Edmund Leach threatened archaeology that he will ‘poison’ it with structuralism, his structuralist work did not have that far reaching impact on the changes of archaeological interpretative paradigms. The reason for that is –
Aleksandar Palavestra
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
La cuarta exclusión. Notas sobre lingüística formal
Lexis, 2015 Formal linguistics is posible only if a program of three exclusions is put into place: exclusion of reference, diachrony and the Subject. The first one to embrace this program was Saussure and then, the different versions of structuralism followed suite.
Mario Montalbetti
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The sctructuralismo as epistemology and method
Revista de estudios teóricos y epistemológicos en política educativa, 2019 The aim of this article is to illustrate the teachers, researchers, academics and students of the Human and Social Sciences, in a general view, but with distinctive features, about history, some theoretical foundations and some final considerations on ...
Luis Francisco Ochoa Rojas
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The Legacy of Structuralism: From Its Dogmas to Methodological Pluralism
SententiaeThere is a widespread idea that the Philosophy Department at University of São Paulo, has been structuralist since the 1960s. In my opinion, this is a myth, the result of a misunderstanding of what structuralism is.
Plínio Junqueira Smith
doaj +1 more source