Results 141 to 150 of about 1,047,704 (361)

Predicting isocitrate dehydrogenase mutation status in glioma using structural brain networks and graph neural networks [PDF]

open access: green, 2021
Yiran Wei   +5 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Analysis of ‘Leading Sectors’: A Long term view of 18 Latin American economies [PDF]

open access: yes
In the 1950s and 60s, in Latin America structuralism was considered as the preeminent form of analysis of economic development and growth. Nowadays, in contrast, as a mode of analysis structuralism is distinctly unfashionable, and has been superceded by ...
Acevedo, Alejandra   +2 more
core   +1 more source

On the Very Idea of a Language of Art: Aesthetics and Common Sense [PDF]

open access: yes, 2017
In a number of writings that were only narrowly circulated, Richard Wollheim took a stand against two pivotal theses at the centre of aesthetic reflection and, above all, of critical and historical-artistic practices: i) that art is a language (and thus ...
Maistrello, Andrea
core  

Structural Harm, Structural Injustice, Structural Repair

open access: yes
Abstract In Chapter 1, ‘Structural Harm, Structural Injustice, Structural Repair’, Jonathan Wolff explores the nature of structural injustice and how it tends to come into being. For Wolff, structural harm is not an injustice but rather a mere unfortunate outcome of structural processes.
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Automatic detection of complex structural genome variation across world populations [PDF]

open access: gold, 2017
Bo Zhou   +13 more
openalex   +1 more source

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