Results 151 to 160 of about 1,047,704 (361)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Carbon nanotube reinforced mortar as a sensor to monitor the structural integrity of restored marble epistyles under shear

open access: diamond, 2016
Zoi S. Metaxa   +5 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Teorins pionjärer

open access: yesLychnos, 2009
From the 1970’s onward, comparative literature has held a unique position among the humanities with regard to the reception, development and application of theory.
Michael Gustavsson
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Minding the Gap: Bias, Soft Structures, and the Double Life of Social Norms [PDF]

open access: yes, 2018
We argue that work on norms provides a way to move beyond debates between proponents of individualist and structuralist approaches to bias, oppression, and injustice. We briefly map out the geography of that debate before presenting Charlotte Witt’s view,
Davidson, Lacey J., Kelly, Daniel
core  

Entre el estructuralismo y su post: modelos de significación en Roland Barthes

open access: yesBajo Palabra, 2016
La obra de Roland Barthes se ha prestado a muy heterogéneas clasificaciones entre las que destacan aquellas que la adscriben al estructuralismo y al postestructuralismo.
R. García Murillo
doaj  

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