Results 211 to 220 of about 1,047,704 (361)

Structural perturbation of chromatin domains with multiple developmental regulators can severely impact gene regulation and development [PDF]

Shreeta Chakraborty, Nina Wenzlitschke, Matthew J. Anderson, Ariel Eraso, Manon Baudic, Joyce J. Thompson, Alicia A Evans, Lilly M Shatford Adams, Raj Chari, Parirokh Awasthi, Ryan Dale, Mark Lewandoski, Timothy J. Petros, Pedro P. Rocha   +13 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Using Queer Theory to Advance Understandings of 'Queer Caregiving' With LGBTQ+ Older Adults. [PDF]

Scand J Caring Sci
Hall S, Oswald A.
europepmc   +1 more source

Engaging with Transformative Paradigms in Mental Health. [PDF]

Int J Environ Res Public Health, 2021
Whitaker L, Smith FL, Brasier C, Petrakis M, Brophy L.   +4 more
europepmc   +1 more source

Review for "Structural disconnectivity from paramagnetic rim lesions is related to disability in multiple sclerosis"

, 2021
Christopher C. Hemond
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Identity, Rurality, and Gender: A Phenomenological Exploration of Rural Nova Scotian Girls' Physical Activity Experiences. [PDF]

Children (Basel)
Tweedie C, Rehman L.
europepmc   +1 more source

L-3-Hydroxyacyl coenzyme-A dehydrogenase – structural studies at 3.5 Å resolution [PDF]

, 1984
Jens J. Birktoft, L.J. Banaszak, Hazel M. Holden, J. B. Alexander Ross, Steven L. Roderick, J.C. Sacchettini, R. Hamlin, N.-H. Xoung   +7 more
openalex   +1 more source

Decision letter for "Tyrosine 288 in the extracellular domain of the human P2X7 receptor is critical for receptor function revealed by structural modelling and site‐directed mutagenesis"

, 2021

openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source