Results 121 to 130 of about 7,023 (306)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Faculty development program evaluation: a need to embrace complexity
Advances in Medical Education and Practice, 2019 Nicolas Fernandez,1 Marie-Claude Audétat21Centre for Pedagogy Applied to the Health Sciences, Department of Family Medicine and Emergency Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada ...
Fernandez N, Audétat MC
doaj
Synthesizing Structuration and Institutional Theory: three cases
, 2001 Research suggests that it is difficult to predict the influence of information technology (IT) on organizations. Using the structuration approach, theorists like Orlikowski suggest technology's effect is context dependent.
Kuhlmeier, David +7 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Desenvolvimento em Questão, 2016 The phenomenon of double hermeneutics, which basically highlights the mutual interpretive interplay between social sciences and activities that constitute its “object” of study, is a central element in the discussions of the English sociologist Anthony ...
Miguel Rivera Peres Júnior +2 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
KEKERASAN SEKSUAL TELEVISI TERHADAP WANITA
Jurnal Ilmu Sosial, 2016 The women’s violence issues is found in adult mass media. What kinds of women violence are found in a children’s televisin program in Indonesia. Gender structuration theory guided this research. It used critical discourse analysis.
Sunarto Sunarto
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Information systems project work in a Saudi organisation : an ethnographic study [PDF]
This study examines IS project trajectories in a Saudi organisation showing how the project is shaped and re-shaped in day-to-day activities. Three project features are adapted to characterise project phenomena: project complexity, embeddedness and ...
Alhazmi, Khaled Awadh H.
core
, 2010 Purpose: The purpose of this paper is to explore how to use structuration theory as a benchmarking tool to analyze the formulation of a national strategy. Design/methodology/approach: The paper presents a longitudinal case study of the telecommunications
Gao, Ping; id_orcid, Li, Jing Hua
core +1 more source