Results 131 to 140 of about 69,658 (298)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Psychological Research in the Multidisciplinary Discourse of Agency: Problems and Prospects

open access: yesВопросы образования
It is shown that the cause of the systemic difficulties experienced by the international mainstream of psychology in developing the problem of agency as a human ability to initiate a change in the environment is that the latter is a phenomenon that has ...
Irina A. Mironenko
doaj   +1 more source

Overcoming restrictive technologies in police call centres: A human agency perspective [PDF]

open access: yes, 2008
Call centres in the police force are restrictive information systems which tend to present call operators with constraints that they need to overcome using their experience in order to offer better services to the public.
Papazafeiropoulou, A   +2 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

As práticas judiciais e o significado do processo de julgamento

open access: yesDados: Revista de Ciências Sociais, 1999
The article suggests that practical reason theory offers the best means to understanding the decision-making process in a trial by jury. More specifically, it argues that the decision-making practices of justice staff are guided by "dually structured ...
Ribeiro Carlos Antonio Costa
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

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