Results 131 to 140 of about 7,023 (306)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
An Algebraic Theory of Structured Objects
Notre Dame Journal of Formal Logic, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
American and European social embeddedness in IS research: the case of structurational approaches.
Whether in Europe or in North America, Structuration Theory has been widely applied in Information System research. Looking at some structurationists’ trajectories, it seems that European and American researchers correspond each to specific sub ...
de Vaujany, François-Xavier
core
[[alternative]]Anthony Giddens' Structuration Theory and Its Implications for Education
, 2010 [[abstract]]Anthony Giddens’ Structuration Theory and Its Implications for Education Abstract This study carries out a comprehensive investigation of Anthony Giddens’ structuration theory on the one hand, and a reflexive elaboration of its implications ...
[[author]]林郡雯 +3 more
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2013 Since 2003, the Radio Frequency Identification System (RFID) technology has gained importance and has been widely applied.
Wu, Mei Ying, Ku, Chun Wei
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Africa Through Structuration Theory - ntu
, 2015 Despite all the talk about African renaissance, much of the continent is plagued by poverty and instability. To break out of that cycle, the guardians of African heritage (the old independence freedom fighters turned political leaders and their ...
Mboyo, Elonga
core +1 more source