Results 111 to 120 of about 5,410,497 (291)

The implications of structuration theory for education. [PDF]

open access: yes, 1989
Thesis (M.Ed.)-University of Natal, 1989.This dissertation is concerned with the implications of the theory of structuration for education. Central to the theory of structuration, is the idea of structuring social relations across time-space, in virtue ...
Naidoo, Pathmaloshini.
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Psychological Research in the Multidisciplinary Discourse of Agency: Problems and Prospects

open access: yesВопросы образования
It is shown that the cause of the systemic difficulties experienced by the international mainstream of psychology in developing the problem of agency as a human ability to initiate a change in the environment is that the latter is a phenomenon that has ...
Irina A. Mironenko
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Theory of Photoluminescence by Metallic Structures

open access: yesACS Nano
Light emission by metals at room temperature is quenched by fast relaxation processes. Nevertheless, Mooradian reported in 1969 the observation of photoluminescence by metals pumped by a laser. Strikingly, while it is currently at the heart of many promising applications, this phenomenon is still poorly understood.
Aurelian Loirette-Pelous   +1 more
openaire   +3 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Structuration Theory and Health and Risk Messaging

open access: yes, 2017
Risk can be defined using a mathematical formula—probability multiplied by consequences. An essential element of risk communication is a focus on messages within organizations.
Tomeka Robinson   +2 more
core   +1 more source

An Algebraic Theory of Structured Objects

open access: yesNotre Dame Journal of Formal Logic, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

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