Results 91 to 100 of about 69,658 (298)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Situating organizational action: the relational sociology of organizations [PDF]

, 2006
This paper advances a relational sociology of organization that seeks to address concerns over how organizational action is understood and situated.
Delbridge, R, Mutch, A, Ventresca, M
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Sundanese Women in Politics: A Structural Analysis to Inform Educational Strategies for Gender Equality

Cakrawala Pendidikan: Jurnal Ilmiah Pendidikan
This study examines Sundanese women's participation in legislative institutions through a structuration theory approach to inform educational strategies for gender equality.
Siti Komariah, Dini Asmiatul Amanah, Muhammad Retsa Rizaldi Mujayapura   +2 more
doaj   +1 more source

Writing new scripts: redefining managerial agency in Cuba [PDF]

Transitional societies are faced with particularly challenging and pressing problems. These usually involve the passage from a centralised, socialist-based society, to a decentralised, market-based economy. This paper addresses a somewhat different case:
Cunha, Miguel Pina e, Cunha, Rita Campus e   +1 more
core  

Situated cultural approach versu predefined cultural archetypes models [PDF]

, 2009
Within the last 20 years, the practical relevance of researching cultural issues, and especially comparing phenomena across cultures, was questioned (Ferraro, 1990).
Ali, M
core  

Developing a framework for the analysis of power through depotentia [PDF]

, 2013
Stakeholder participation in tourism policy-making is usually perceived as providing a means of empowerment. However participatory processes drawing upon stakeholders from traditionally empowered backgrounds may provide the means of removing empowerment
Bachrach P., Bickerstaff K., Bramwell B., Bronia C. Hall, Church A., Church A., Coles T., Dahl R., Everett J., Foucault M., Friedman A. L., Gill A. M., Hall C. M., Hardy C., Heyward C., Jamal T., Jamal T., Lowndes V., Lukes S., Lukes S. (Ed.)., Mitchell R. K., Morriss P., Rowley T. J., Shepsle K. A., Short C., Silva L., Timothy D. J.   +26 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The structuration theory of Anthony Giddens: a brief reading of some influences arising from the sociological literature

Revista Sem Aspas, 2015
This article is intended to conduct a reading on the structuration theory of Anthony Giddens in order to identify some points of influence of the sociological literature - developed until then - on his theory.
Tailon Rodrigues Almeida
doaj  

Artefact Ecologies: Supporting Embodied Meeting Practices with Distance Access [PDF]

, 2007
Frameworks such as activity theory, distributed cognition and structuration theory, amongst others, have shown that detailed study of contextual settings where users work (or live) can help the design of interactive systems.
Dix, Alan, Vyas, Dhaval
core   +2 more sources