Results 91 to 100 of about 5,429,668 (289)
Conceptualizing Interaction with ERP Systems Using Adaptive Structuration Theory [PDF]
The new brand of Information Systems (IS) is Enterprise Resource Planning (ERP) and while lots of studies have used functional and networking type IS to operationalize adoption (or system usage) measures, ERP systems have yet to mature in that area ...
Tan, Felix, Sedera, Darshana
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
STRUCTURATION THEORY AND INFORMATION SYSTEMS RESEARCH [PDF]
Research on the social and organizational aspects of information systems often lacks an adequate theoretical and methodological basis. In this paper, we propose that structuration theory provides a broad conception of social action and human society ...
Walsham, Geoff, Han, Chun-Kwong
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Social Media and Web 2.0 tools have dramatically increased the amount of previously private data that users share on the Web; now with the advent of GPS-enabled smartphones users are also actively sharing their location data through a variety of ...
Zafeiropoulou, Aristea M. +3 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
This study examines Sundanese women's participation in legislative institutions through a structuration theory approach to inform educational strategies for gender equality.
Siti Komariah +2 more
doaj +1 more source
COMMUNICATION FUNCTIONS OF SOUTH AFRICA APARTHEID AND THE U.S. MEXICO SECURITY FENCE [PDF]
Powerful semiotic signs like the Great Wall of China and the Berlin Wall served significant communicative functions. The modern culture of nation state wall building continues despite the fact that the security fences are obsolete.
Thornton, Tyler J.
core

