Results 71 to 80 of about 5,429,668 (289)

On the theory of graded structures

open access: yesJournal of Symbolic Computation, 1986
A new structural algebraic framework is given to the concept and the construction of the generalized standard bases. Graded structure over a commutative ring \(A\), \(v\)-filtered structure on \(A\), modules over a graded structure, modules on the \(v\)-filtered structures and the corresponding morphisms as well as their relationship are considered ...
openaire   +1 more source

Structural Proof Theory as Rewriting [PDF]

open access: yes, 2006
The multiary version of the λ-calculus with generalized applications integrates smoothly both a fragment of sequent calculus and the system of natural deduction of von Plato. It is equipped with reduction rules (corresponding to cut-elimination/normalisation rules) and permutation rules, typical of sequent calculus and of natural deduction with ...
José Espírito Santo   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Rethinking structuration logics in socio-technical transitions theory

open access: yes, 2022
This paper revisits the multi-level perspective (MLP) of socio-technical transition theory from the point of view of one of its early foundations, Giddens’ theory of structuration.
Hansen, Teis, Stalmokaitė, Ignė
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Uses of Giddens' Structuration Theory [PDF]

open access: yes, 1999
: Anthony Giddens has made claims for the utility of structuration theory. These claims present structuration theory as a contributant to the post-empiricist reconstruction of theory and application in social science, and, consequently, as ajustification
Bryant, Christopher G.A.
core   +2 more sources

Agência humana e estrutura a partir da Teoria da Estruturação

open access: yesCiências Sociais Unisinos, 2015
Permanent changes of social life require reflections that address the contextualized individual actions and collective transformative reality. The theory of structuring ponders individual action and the course of collective action, trying to break the ...
Flavia Galindo
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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