Results 81 to 90 of about 69,658 (298)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Why doesn't integrated care work? Using Strong Structuration Theory to explain the limitations of an English case. [PDF]
Sociol Health Illn, 2022 Hughes G, Shaw SE, Greenhalgh T.
europepmc +1 more source
Implications of transforming the Patient Record into a Knowledge Management System [PDF]
In this paper I theorize about how transforming the interpretative scheme for what a patient record is might restructure a health care setting. The observations presented here were obtained when I during three years followed implications of constructing ...
Beckerman, Carina
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Limitations of risk-based artificial intelligence regulation: a structuration theory approach
Discover Artificial IntelligenceArtificial Intelligence (AI) is transforming the way we live and work. The disruptive impact and risks of Generative AI have accelerated the global transition from voluntary AI ethics guidelines to mandatory AI regulation.
Lily Ballot Jones +2 more
doaj +1 more source
Cultural universality versus particularity within e-CRM systems: a special case of information systems [PDF]
, 2005 Cultural factors are often identified as a crucial influence on the success or failure of Information Systems in general and Electronic Customer Relationship Management Systems (eCRM) in particular.
Ali, M, Alshawi, S
core
Designing new socio-economic imaginaries [PDF]
, 2019 This short paper recovers the term ‘imaginaries’ which is often used in the social sciences to describe a meaning system that frames individuals lived experience of an inordinately complex world. The paper goes on to reflect on the extent to which design
Mehrpouya, Hadi +5 more
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cooperation for climate adaptation in tourism
Revue de Géographie Alpine, 2013 Climate change is an imminent challenge for many alpine tourism destinations. While the effects of changing climatic patterns are well documented with respect to the physical geographical sphere, research into the effects of climate change upon the ...
Romano Wyss
doaj +1 more source
Systemic effector conceptual model in groupware implementation [PDF]
, 2007 Network software systems and groupware within organizations differ from other information technologies, requiring individuals to 'design' their own use.
Hassall, John
core +1 more source