Results 81 to 90 of about 5,410,497 (291)
Why doesn't integrated care work? Using Strong Structuration Theory to explain the limitations of an English case. [PDF]
Sociol Health Illn, 2022 Hughes G, Shaw SE, Greenhalgh T.
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Limitations of risk-based artificial intelligence regulation: a structuration theory approach
Discover Artificial IntelligenceArtificial Intelligence (AI) is transforming the way we live and work. The disruptive impact and risks of Generative AI have accelerated the global transition from voluntary AI ethics guidelines to mandatory AI regulation.
Lily Ballot Jones +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Leaving Nothing to Chance: Modeling the Proactive Structuration of a New Technology [PDF]
Adaptive structuration theory (AST, DeSanctis and Poole 1994) describes how people come to understand and use a technology. In this paper we develop the idea of proactive structuration--how social networking can be proactively managed in order to speed ...
Fuller, Mark A. +2 more
core
, 2002 This chapter argues that the three most commonly used perspectives in conducting research on business-to-business (B2B) eCommerce-transaction cost economics, electronic market hypothesis, and network analysis-have inadequately explained the unfolding ...
Pavlou, Paul A. +3 more
core +1 more source
Improvising information technology projects through the duality of structure
South African Journal of Information Management, 2017 Background: There is always emphasis on information technology (IT) projects because of their significance in organisations. Thus, efforts and resources are reciprocally committed to ensure the successes.
Tiko Iyamu
doaj +1 more source
CoRR, 2018 We develop a novel formal theory of finite structures, based on a view of finite structures as a fundamental artifact of computing and programming, forming a common platform for computing both within particular finite structures, and in the aggregate for computing over infinite data-types construed as families of finite structures. A "finite structure"
openaire +3 more sources
Operational theories as structural realism
Studies in History and Philosophy of Science, 2022 We undertake a reconstruction of the epistemic significance of research on operational theories in quantum foundations. We suggest that the space of operational theories is analogous to the space of possible worlds employed in the possible world semantics for modal logic, so research of this sort can be understood as probing modal structure.
openaire +4 more sources