Results 61 to 70 of about 68,987 (297)
Designing new socio-economic imaginaries [PDF]
, 2019 This short paper recovers the term ‘imaginaries’ which is often used in the social sciences to describe a meaning system that frames individuals lived experience of an inordinately complex world. The paper goes on to reflect on the extent to which design
Mehrpouya, Hadi +5 more
core +3 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Transylvanian Review of Administrative Sciences, 2016 The massive shift to virtual modalities and functions has changed the context of leadership and organizational structures, and thus how leadership is exercised. To date, the fi elds of e-leadership and e-management, or more generally, virtual leadership,
Montgomery VAN WART +2 more
doaj
Cooperation for climate adaptation in tourism
Revue de Géographie Alpine, 2013 Climate change is an imminent challenge for many alpine tourism destinations. While the effects of changing climatic patterns are well documented with respect to the physical geographical sphere, research into the effects of climate change upon the ...
Romano Wyss
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
"This does my head in". Ethnographic study of self-management by people with diabetes
BMC Health Services Research, 2012 Background Self-management is rarely studied 'in the wild'. We sought to produce a richer understanding of how people live with diabetes and why self-management is challenging for some.
Hinder Susan, Greenhalgh Trisha
doaj +1 more source
Situated cultural approach versu predefined cultural archetypes models [PDF]
, 2009 Within the last 20 years, the practical relevance of researching cultural issues, and especially comparing phenomena across cultures, was questioned (Ferraro, 1990).
Ali, M
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
ANÁLlSE ESTRUTURACIONISTA DE POLíTICAS PÚBLICAS: a dualidade da política pública
Revista de Políticas Públicas, 2013 The paper proposes to justify the creatlon 01 an analysis unlt: the duality 01 publlc poücy. It argues that thls analysis unít can reveal the rules and resources 01 techno-bureaucratic structure, and values relating to polítical actlon, which in turn ...
Lucas Canestri de Oliveira +2 more
doaj
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source