Results 61 to 70 of about 3,470,734 (212)

Anticancer Profile of Rhodanines: Structure–Activity Relationship (SAR) and Molecular Targets—A Review

Molecules, 2022
The rhodanine core is a well-known privileged heterocycle in medicinal chemistry. The rhodanines, as subtypes of thiazolidin-4-ones, show a broad spectrum of biological activity, including anticancer properties. This review aims to analyze the anticancer
Jacek Szczepański, Helena Tuszewska, Nazar Trotsko   +2 more
doaj   +1 more source

Design, Synthesis and Antifungal Activity of Psoralen Derivatives

Molecules, 2017
A series of linear furanocoumarins with different substituents have been designed and synthesized. Their structures were confirmed by 1H-NMR spectroscopy, high resolution mass spectra (EI-MS), IR, and X-ray single-crystal diffraction.
Xiang Yu, Ya Wen, Chao-Gen Liang, Jia Liu, Yu-Bin Ding, Wei-Hua Zhang   +5 more
doaj   +1 more source

Orientation dependence of ferroelectric properties of pulsed-laser-ablated Bi4-xNdxTi3O12 films [PDF]

, 2003
Epitaxial (001)-, (118)-, and (104)-oriented Nd-doped Bi4Ti3O12 films have been grown by pulsed-laser deposition from a Bi4-xNdxTi3O12 (x=0.85) target on SrRuO3 coated single-crystal (100)-, (110)-, and (111)-oriented SrTiO3 substrates, respectively.
Barber, Z. H., Dawber, M., Garg, A., Lightfoot, P., Scott, J. F., Snedden, A.   +5 more
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Whey-derived peptides interactions with ACE by molecular docking as a potential predictive tool of natural ACE inhibitors [PDF]

, 2020
Several milk/whey derived peptides possess high in vitro angiotensin I-converting enzyme (ACE) inhibitory activity. However, in some cases, poor correlation between the in vitro ACE inhibitory activity and the in vivo antihypertensive activity has been ...
Chamata, Yara, Jauregi, Paula, Watson, Kimberly A.   +2 more
core   +1 more source

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections [PDF]

, 2018
Indexación: Scopus.A rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics and reducing the therapeutic arsenal available for treatment of infectious diseases. In the present study, we developed a new class
Alarcón, P., Andrades-Lagos, J., Bollo Dragnic, S., Campanini-Salinas, J., Choquesillo-Lazarte, D., Faúndez, M., Gonzalez Rocha, G., Kogan, M., Mella, J., Recabarren Gajardo, G., Salas-Huenuleo, E., Silva, F., Vidal, R., Vásquez-Velásquez, D.   +13 more
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Research Progress on Structure Characteristics, Biological Activity, Structure-Activity Relationship and Product Development of Dendrobium Polysaccharides

Shipin gongye ke-ji
Dendrobium is a traditional, valuable, and nourishing medicinal herb in China. It benefits the stomach, promotes fluid production, nourishes Yin, and clears heat. Polysaccharides are among the main active ingredients of Dendrobium.
Zhaoyong LUO, Yan JIANG, Xiaoli YU, Jinglei LIU, Boning LI, Keying ZHANG, Shuling WANG, Tian XIE   +7 more
doaj   +1 more source

Structure-activity relationship studies on O-sulfated Hirudins [PDF]

, 1998
Thesis (Ph. D. in Agriculture)--University of Tsukuba, (B), no.
Muramatsu Ryo, 村松 了
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Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
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Bioinformatics, bacterial expression and enzyme activity analyses of dichloromethane dehalogenase from Methylobacterium rhodesianum H13

Biotechnology & Biotechnological Equipment, 2020
Dechlorination is the key step in biological degradation of dichloromethane (DCM), which is catalyzed by the enzyme DCM dehalogenase. In this study, the detailed structure and function of DCM dehalogenase in Methylobacterium rhodesianum H13 were ...
Jianguo Ni, Ying Liu, Chenjia Shen, Dongzhi Chen, Yueyong Xin, Qi Liu   +5 more
doaj   +1 more source

A practical overview of quantitative structure-activity relationship [PDF]

, 2009
Quantitative structure-activity relationship (QSAR) modeling pertains to the construction of predictive models of biological activities as a function of structural and molecular information of a compound library.
Isarankura-Na-Ayudhya, Chartchalerm, Naenna, Thanakorn, Nantasenamat, Chanin, Prachayasittikul, Virapong   +3 more
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