Results 41 to 50 of about 17,685,797 (244)

An Insight into Antihyperlipidemic Effects of Polysaccharides from Natural Resources

Molecules, 2022
Hyperlipidemia is a chronic metabolic disease caused by the abnormal metabolism of lipoproteins in the human body. Its main hazard is to accelerate systemic atherosclerosis, which causes cerebrovascular diseases such as coronary heart disease and ...
Yong-Shuai Jing, Yun-Feng Ma, Fei-Bing Pan, Ming-Song Li, Yu-Guang Zheng, Lan-Fang Wu, Dan-Shen Zhang   +6 more
doaj   +1 more source

Improvement of the Oxidative Stability of Rosehip, Hemp, and Passion Fruit Oils by the Addition of Monocyclic Phenols as Antioxidants

Antioxidants
Caffeic, syringic, and protocatechuic acids are phenolic acids with important antioxidant activity. In this work we studied how the oxidative stability of rosehip, hemp, and passion fruit oils improves with the addition of these antioxidant acids.
Gloria Castellano, Irene Sarrión, Carmen Fagoaga, Ricardo M. Giménez-Núñez, Enrique Gómez-Gómez, Francisco Torrens   +5 more
doaj   +1 more source

MOESM1 of Quantitative structureâ activity relationship to predict the anti-malarial activity in a set of new imidazolopiperazines based on artificial neural networks

, 2019
Additional file 1.Additional tables.
Yousefinejad, Saeed, Mahboubifar, Marjan, Eskandari, Rayhaneh   +2 more
openaire   +1 more source

MOESM1 of Molecular docking, synthesis, kinetics study, structureâ activity relationship and ADMET analysis of morin analogous as Helicobacter pylori urease inhibitors

, 2019
Additional file 1. Supplementary file for spectral data.
Kataria, Ritu, Khatkar, Anurag
openaire   +1 more source

Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP

Drug Design, Development and Therapy, 2022
Lijing Wang College of Life Sciences and Technology, China Pharmaceutical University, Nanjing, Jiangsu, People’s Republic of ChinaCorrespondence: Lijing Wang, College of Life Science and Technology, China Pharmaceutical University, 639 Longmian ...
Wang L
doaj  

Semi-Synthesis of Harringtonolide Derivatives and Their Antiproliferative Activity

Molecules, 2021
Harringtonolide (HO), a natural product isolated from Cephalotaxus harringtonia, exhibits potent antiproliferative activity. However, little information has been reported on the systematic structure−activity relationship (SAR) of HO derivatives ...
Xiutao Wu, Lijie Gong, Chen Chen, Ye Tao, Wuxi Zhou, Lingyi Kong, Jianguang Luo   +6 more
doaj   +1 more source

MOESM1 of 4-Thiazolidinone coumarin derivatives as two-component NS2B/NS3 DENV flavivirus serine protease inhibitors: synthesis, molecular docking, biological evaluation and structureâ activity relationship studies

, 2018
Additional file 1. Additional figures and Tables.
Yusufzai, Samina, Osman, Hasnah, Khan, Mohammad, Abd Razik, Basma, Ezzat, Mohammed, Mohamad, Suriyati, Sulaiman, Othman, Gansau, Jualang, Parumasivam, Thaigarajan   +8 more
openaire   +1 more source

Expedient Synthesis of a Library of Heparan Sulfate Like “Head to Tail” Linked Multimers for Structure and Activity Relationship Studies [PDF]

, 2022
Heparan sulfate (HS) plays significant roles in various biological processes such as inflammation, cell proliferation, and bacterial and viral infection. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of
Chang-xin, Huo, Fuming, Zhang, Kedar, Baryal, Linda, Hsieh-wilson, Li, Liang, Weizhun, Yang, Jian, Liu, Xuefei, Huang, Jicheng, Zhang, Robert, Linhardt, Sherif, Ramadan, Jamie, Bernard   +11 more
core   +1 more source

Recent advances in the structure and immunomodulatory activity of food-derived glycoprotein complex

Journal of Future Foods
Glycoprotein complexes, a kind of structural biomolecules, are characterized by extensive functions, such as immunomodulatory and anti-inflammatory activities.
Yu Zhong, Jiangxiong Zhu, Bifen Zhu, Hao Yin, Danfeng Wang, Yun Deng, Minyan Zhang, Chunrong Zhang   +7 more
doaj   +1 more source

Synthesis and Structure-Activity Relationship Studies of C(13)-Desmethylene-(−)-Zampanolide Analogs [PDF]

, 2023
We have prepared a series of partially reduced or demethylated analogs of the natural microtubule stabilizer (−)-zampanolide and we have assessed their antiproliferative activity, their microtubule-binding affinity and their effects on the cellular ...
Simone, Berardozzi, Bernhard, Pfeiffer, John H., Miller, Sandro, Pagani, Mariano, Redondo-Horcajo, J. Fernando, Díaz, Daniel, Lucena-Agell, Karl-Heinz, Altmann, Tobias Michael, Brütsch, Etienne, Cotter, Carolina, Davies   +10 more
core   +1 more source