Results 31 to 40 of about 17,685,797 (244)

Synthesis and Antibacterial Evaluation of N-phenylacetamide Derivatives Containing 4-Arylthiazole Moieties

Molecules, 2020
A series of new N-phenylacetamide derivatives containing 4-arylthiazole moieties was designed and synthesized by introducing the thiazole moiety into the amide scaffold.
Hui Lu, Xia Zhou, Lei Wang, Linhong Jin
doaj   +1 more source

Synthesis and leishmanicidal activity of cinnamic acid esters: structure–activity relationship [PDF]

, 2014
Several cinnamic acid esters were obtained via Fischer esterification of cinnamic acids derivatives with aliphatic alcohols. Structures of the products were elucidated by spectroscopic analysis.
Vélez, Iván D., Robledo, Sara M., Diaz-Oltra, Santiago, Cardona G, Wilson I, Paños Pérez, Julián, Cardona Galeano, Wilson Isidro, Muñoz, Diana, Otero, Elver, Carda, Miguel   +8 more
core   +1 more source

Design, Synthesis, and Anti-Inflammatory Activities of 12-Dehydropyxinol Derivatives

Molecules, 2023
Pyxinol skeleton is a promising framework of anti-inflammatory agents formed in the human liver from 20S-protopanaxadiol, the main active aglycone of ginsenosides. In the present study, a new series of amino acid-containing derivatives were produced from
Yunxiao Wang, Xiaoliang Mi, Yuan Du, Shuang Li, Liping Yu, Meng Gao, Xiaoyue Yang, Zhihua Song, Hui Yu, Gangqiang Yang   +9 more
doaj   +1 more source

Additional file 4: of PubChem structureâ activity relationship (SAR) clusters

, 2015
(supplementary_data.pdf): contains Figures S1, S2, and S3.
Sunghwan Kim, Lianyi Han, Yu, Bo, HäHnke, Volker, Bolton, Evan, Bryant, Stephen   +5 more
openaire   +1 more source

Prediction of mammalian toxicity by quantitative structure-activity relationships - aliphatic amines and anilines

, 2022
S.198-204 : Abb.,Tab.Quantitative Structure-Activity Relationships (QSARs) are derived to predict oral toxicity data of aliphatic amines and anilines for rats.
Klein, W., Jäckel, H.
core   +1 more source

Progress in the Optimization of 4(1H)-Quinolone Derivatives as Antimalarials Targeting the Erythrocytic, the Exoerythrocytic and the Transmitting Stages of the Malaria Parasite

CHIMIA, 2017
Malaria is one of the leading infectious diseases occurring mainly in tropical and subtropical areas. Although available antimalarial tools have reduced the number of fatalities, there is still an urgent need for the development of new and more ...
Fabian Brockmeyer, Roman Manetsch
doaj   +1 more source

MOESM1 of Structureâ activity relationships in a series of antiplasmodial thieno[2,3-b]pyridines

, 2019
Additional file 1. Molecular structures, details of the syntheses and purification procedures as well as characterization data of all new products.
Masch, Andreas, Nasereddin, Abed, Alder, Arne, Bird, Megan, Schweda, Sandra, Preu, Lutz, Doerig, Christian, Dzikowski, Ron, Gilberger, Tim, Kunick, Conrad   +9 more
openaire   +1 more source

Pyrimidine: a review on anticancer activity with key emphasis on SAR

Future Journal of Pharmaceutical Sciences, 2021
Background Cancer is a global health challenge, it impacts the quality of life and its treatment is associated with several side effects. Resistance of the cancer cells to the existing drugs has led to search for novel anticancer agents.
Aastha Mahapatra, Tanya Prasad, Tripti Sharma   +2 more
doaj   +1 more source

Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Inflammation and disease are closely related. Inflammation can induce various diseases, and diseases can promote inflammatory response, and two possibly induces each other in a bidirectional loop.
Ming Bian, Qian-qian Ma, Yun Wu, Huan-huan Du, Gong Guo-hua   +4 more
doaj   +1 more source

Structure Features of Peptide-Type SARS-CoV Main Protease Inhibitors: Quantitative Structure Activity Relationship Study [PDF]

, 2020
In the present work, an extensive QSAR (Quantitative Structure Activity Relationships) analysis of a series of peptide-type SARS-CoV main protease (MPro) inhibitors following the OECD guidelines has been accomplished.
Vesna, Rastija, Meghshyam K., Patil, Ajaykumar, Gandhi, Vijay, Masand   +3 more
core   +1 more source