Results 41 to 50 of about 675,511 (236)

Quantitative structure-property relationship studies on n-octanol/water partitioning coefficients of PCDD/Fs [PDF]

open access: yes, 2001
Based on some fundamental quantum chemical descriptors computed by PM3 Hamiltonian, by the use of partial least-squares (PLS) analysis, a significant quantitative structure-property relationship (QSPR) model for logK(ow) of polychlorinated dibenzo-p ...
Jingwen Chen   +5 more
core  

Application of quantitative structure property relationship to the design of high refractive index 193i resist [PDF]

open access: yes, 2008
A robust quantitative structure property relationship (QSPR) model with five parameters has been developed from 126 organic compounds for the prediction of refractive index at 589 nm.
Conley, Willard   +9 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The relationship of geographical indications with real property valuation and management [PDF]

open access: yes, 2007
Purpose - The purpose of this paper is to examine the relationship of geographical indications (GIs) with real property valuation and management. Design/methodology/approach - The paper considers existing and developing legal frameworks and current ...
Blackwell, M.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Historical Analysis [PDF]

open access: yes, 2019
This chapter provides a brief account of the history of family property law in New Zealand from the nineteenth century to the present day, in the context of relationship property on ...
Briggs, Margaret
core   +2 more sources

Spatial heterogeneity as the structure feature for structure–property relationship of metallic glasses

open access: yesNature Communications, 2018
Directly relating the mechanical properties of metallic glasses to their atomic structure remains a challenge. Here, the authors use high resolution microscopy to show many mechanical properties of metallic glasses depend on a single structural parameter,
Fan Zhu   +4 more
doaj   +1 more source

Influence of molten-pool cooling rate on solidification structure and mechanical property of laser additive manufactured Inconel 718

open access: yesJournal of Materials Research and Technology, 2022
The relationship between solidification structure and cooling rate is critical for optimizing processing parameters to achieve desired mechanical property of additive manufactured parts.
Hui Xiao   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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