Results 111 to 120 of about 5,517,395 (407)
Antioxidant and Antidiabetic Effects of Flavonoids: A Structure-Activity Relationship Based Study
BioMed Research International, 2017 The best described pharmacological property of flavonoids is their capacity to act as potent antioxidant that has been reported to play an important role in the alleviation of diabetes mellitus.
Murni Nazira Sarian +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Molecules, 2010 Five new pimarane diterpenoids 1-5 were synthesized using ent-8(14)-pimarene-15R,16-diol as starting material. The structures were elucidated by means of extensive NMR and MS analysis.
Dan-Qing Feng +4 more
doaj +1 more source
Learning material synthesis-process-structure-property relationship by data fusion: Bayesian Coregionalization N-Dimensional Piecewise Function Learning [PDF]
arXiv, 2023 Autonomous materials research labs require the ability to combine and learn from diverse data streams. This is especially true for learning material synthesis-process-structure-property relationships, key to accelerating materials optimization and discovery as well as accelerating mechanistic understanding.
arxiv
Structure–activity relationship of amyloid fibrils [PDF]
FEBS Letters, 2009 Protein aggregation is a process in which proteins self‐associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as either amorphous or highly ordered, the most common form of the latter being amyloid fibrils. Amyloid fibrils composed of cross‐β‐sheet structure are the pathological hallmarks of several diseases ...
Jason Greenwald +3 more
openaire +3 more sources
Relaxin family peptides: structure–activity relationship studies
British Journal of Pharmacology, 2017 The human relaxin peptide family consists of seven cystine‐rich peptides, four of which are known to signal through relaxin family peptide receptors, RXFP1–4.
N. Patil +5 more
semanticscholar +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF AMIDE DERIVATIVES FROM ACRYLOPIMARIC ACID
BioResources, 2012 This paper reports on the synthesis of a series of amide derivatives from acrylopimaric acid (APA). The derivatives contained aromatic groups and were characterized by IR, 1HNMR, MS, and elemental analysis.
Jian Li, +4 more
doaj
Molecular Oncology, EarlyView.The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source